期刊名称：DNA SEQUENCE
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
DNA Sequence will accept original high quality reports based on mapping, sequencing and analysis of DNA and RNA, irrespective of supporting biological or functional data. Acceptable reports may describe coding or non-coding features of a single locus or whole genomes. Features of interest include e.g. genes (incl. RNA genes), variation, promoters, epigenetic modifications and any features affecting DNA/RNA function, structure and evolution. Experimental and computational method reports on the above topics are equally acceptable.
Abstracting Information:
DNA Sequence is abstracted in: Current Contents?Life Sciences; Science Citation Index? SciSearch? Research Alert? Biochemistry and Biophysics Citation Index? Current Awareness in Biological Science (CABS); Chemical Abstracts; Index Medicus/Medline/Genbank and Zoological Record, UK
Instructions to Authors
TYPES OF CONTRIBUTIONS
Full-length research papers - As a guide full length research papers should normally occupy six to ten printed pages (approximately 4000-7000 words) but may be longer depending on the length of the sequence figures.
Short communications - between one and four pages (not more than 2500 words) including up to 4 figures and tables and twenty references. They are expected to be reports of complete, not preliminary studies.
Scientific correspondence - designed to provide a mechanism for the exchange of practical information, advice and opinions. The opinions and advice expressed are not necessarily those of the editors or the Journal and are published at the discretion of the editors.
Review articles - commissioned, or submitted on topics of current interest. Suggestions are welcomed but where submission is without prior invitation, authors should send a summary of the article for consideration by the Editor-in-Chief before commencing detailed work on the manuscript. The format of the review is left to the author's discretion but should include a suitable list of key words or phrases and should not exceed 10 printed pages.
SUBMISSION OF MANUSCRIPTS
All manuscripts should be submitted to the Editor-in-Chief, Dr Stephan Beck, DNA Sequence Editorial Office, Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK (Email: dnasequence@sanger.ac.uk; Fax +44 01223 494919) All manuscripts should preferably be sent in pdf format, converted from Word doc.
Authors are encouraged to submit their papers on disk. Disks must be accompanied by four hard copies (the original plus three copies). The publisher cannot return disks after use. Manuscripts should be of letter quality, in double spacing throughout, using only one side of the paper.
Submission of a paper to DNA Sequence will be taken to imply that it represents original work not previously published, that it is not being considered elsewhere for publication, and that if accepted for publication it will not be published elsewhere in the same form, in any language, without the consent of the editor and Publisher. If previously published tables, illustrations or more than 200 words of text are to be included, then the copyright holder's permission should be obtained. Copies of any such permission letters must accompany the manuscript.
FORMAT AND PRESENTATION
Papers should be written concisely in English. They should be typed double-spaced, with wide margins on one side of A-paper. Non-standard abbreviations should be defined in the text when first used. SI units and abbreviations are preferred as recommended by the IUPAC-IUB Commission on Biochemical Nomenclature (Biochemical Nomenclature and Related Documents, Biochemical Society, UK). Enzyme nomenclature should follow that given in Enzyme Nomenclature (1980), Academic Press: New York, Genetic loci and the first three letters of restrictions enzymes should be underlined to indicate italics.
Short communications should include an abstract but contain no headings. Experimental detail should be given in figure legends. If new experimental procedures are reported they can be presented in the form of a figure or table. Research papers should be presented in the following order.
(a) Title Page - This initial page should contain the full paper title plus a shortened version for running heads. Authors' names and affiliations should appear exactly as required in the final paper and the author for correspondence should be indicated with a full postal address, telephone and fax numbers, and email address where possible.
(b) Abstract - Each paper requires an abstract of 100-150 words summarizing the significant coverage and findings. There should also be up to six indexing key words.
(c) Introduction, Materials and methods, Results, Discussion, Acknowledgements - Main text should be typed without design (no bold or italic) flush left and unjustified. Italics within the text may be indicated by underlining. First, second and third level headings can be differentiated by marking them with A, B or C respectively in the margin by the heading. Headings should be separated from the main body of the text by one line. Personal acknowledgements should precede those for institutions or agencies. (d) References - References and notes should be indicated in the text by the Harvard system. The full list should be collected and typed at the end of the paper in alphabetical order. References should be complete in all details and follow the style below for a journal article (Kouzarides et al, 1987) or book chapter (Bankier et al., 1988). Note that the full titles of journals should be given.
Bankier A.T., Weston K.M., and Barrell B.G. (1988). Random cloning and sequencing by the M13/dideoxynucleotide chain termination method. In Wu R. (ed). Methods in Enzymology (London: Academic Press), pp. 51-93.
Kouzarides T., Bankier A.T., Satchwell S.C., Weston K. M. Tomlinson P. and Barrell B.G. (1987). Large-scale Rearrangement of Homologous Regions in the Genomes of HMCV and EBV. Virology 157, 397-413.
Unpublished results (including articles submitted for publication) or personal communications should be cited as such within the text and substantiated by a letter of permission. Abstracts of papers presented at meetings may not be cited.
It is assumed that, with the development of the World Wide Web (WWW), authors and/or the publisher will propose distribution of articles or parts of articles on the WWW. If the author knows the HTTP address of a referenced article on the WWW, this information should be added at the end of the reference. Please use the following style
where http://www.blouk.com/article.html is the HTTP address.
(e) Tables - These should be numbered consecutively with arabic numerals and given a clear caption. The use of vertical lines should be avoided. Table footnotes should be typed below the table and designated by superior lower case letters. An indication should be placed in the margin of the manuscript at a point appropriate for insertion of the table.
(f) Figures - All figures should be numbered with consecutive arabic numbers, have descriptive legends printed separately from the figure. All figures should be referred to in the text (see paragraph on Text Call-outs) and an indication should be placed in the manuscript margin near the ideal site for the figure.
Preparation: All original figures, including chemical formulae, should be of a high quality, suitable for direct reproduction. These should accompany the first copy of the manuscript, those in the second and third replicas of the manuscript may be photocopies. Line drawings should be in black on white paper, with all lettering and symbols included. Alternatively, good, sharp photoprints ('glossies') are acceptable. Photographs intended for halftone reproduction must be high-quality, glossy original prints of maximum contrast. Each figure should be clearly labelled with the figure number and author name. The top should be labelled in cases which may cause confusion. Redrawing or retouching of unusable figures will be charged to authors.
Size: Figures should be planned so that they reduced to 8 cm column width. The preferred width of line drawings is 16.5 cm with capital lettering 4 mm high, for reduction by one-half. Photographs for halftone reproduction should be about twice the desired size.
Colour Plates: A limited number of colour plates and figures will be considered and printed free of charge if and when it is deemed necessary to the research. In certain cases it may be necessary to reproduce colour plates in black and white in the print copy of the journal, though plates can be reproduced in colour, in the online edition, upon request.
Sequence Figures: Sequence figures may occupy one column width (80 mm) or double column width (165 mm). Nucleoticle sequences with a translation of amino acid sequences in the one letter code should be of 60 or 120 characters respectively. All sequences should be numbers beginning at one (1). Sequences should not contain negative numbers. Where the coding sequence is only one strand then only that strand need be shown. When coding is on both strands then both strands should be shown with the amino acid sequence displayed above or below the nucleoticle sequence as appropriate. Amino acid sequences should be displayed in the one letter code. Sequences should not be split up into groups eg, groups of ten, but should be evenly spaced. Long sequence figures may need to be in the form of an appendix at the end of the paper in order not to interrupt the text.
Feature Table: Where a number of features in the sequence are discussed in the text then a simple feature table should be included which summarizes the relevant features and their position in the sequence.
This table should be in the form:
| Feature |
From |
To |
Stand |
Comments |
Features should show for example the position of transcription signals, coding regions including the boundaries of introns and exons, variation, conflicts with previously published sequences and any other biologically significant feature of the sequence which is discussed in the text. To distinguish between strands, use C for complementary strand in the table
Text call-outs to figures, tables and other elements are the basis for searching articles on electronic delivery. Therefore, proper designation of text call-outs to figures and other elements is essential to the success of electronic delivery. When referring to a figure, table or other element within an article, always call the element by its full name: "See Table 1", "Figure 1 illustrates", "Refer to Scheme 1". Do not use ambiguous call-outs (for example, "1 illustrates_") that do not clearly denote the element being referred to.
DATABASE SUBMISSION OF SEQUENCE
It is a prerequisite that the sequence must be submitted to the EMBL, Genbank or DDBJ database and an accession number obtained before it can be published by the Journal. The databases require a sequence to be submitted in computer readable form. This can be done by electronic file transfer (email), floppy disk or by using a submission system through the World Wide Web at http://www.ebi.ac.uk/
Sequence Data Submission forms are obtained by:
1 . Sending an email message containing the command 'GET DOC:DATASUB.TXT' to Netserv@ebi.ac.uk
2. Sending a mail or fax request to: EMBL Nucleoticle Sequence Submissions, European Bioinformatics Institute, Hinxton Hall, Hinxton, Cambridge CB10 1RQ, UK, Fax: (+44) 1223 494468. Tel: (+44) 1223 494437.
The filled submission forms should be mailed to the above address, or (preferably) sent by email to DATSUBS@EBI.AC.UK. The information will be shared among the following databases:
EMBL Data Library (Heidelberg, Germany)
DNA DataBank of Japan (DDBJ; Mishima, Japan)
GenBank (Los Alamos, NM, USA and Mountain View, CA, USA)
Institute for Protein Sequence Data Resource (NBRF-PIR; Washington, D.C. USA)
International Protein Information Database in Japan (JIPID; Noda, Japan) National
Biomedical Research Foundation Protein Identification Martinsried (MIPS; Martinsried, Germany)
The EMBL Data Library has established a PCR primers database. This information is not mandatory but EMBL Data Library has requested that we recommend to authors that they supply this information.
There are currently two ways for submitting information to the PCR primers database; the easier and much preferred way is through the WWW, by using a client that supports forms (e.g. Mosaic or Netscape). The submission system may be accessed from the PCR primers database home page at, http://www.ebi.ac.uk/dbases/primers/primers_home.html. Users who do not have access to the WWW but do have email may fill in an electronic submission form which can be sent by email or on a disk to the database. Users who know how to use the ftp protocol, can download the form by anonymous ftp to ftp.ebi.ac.uk. Users who are limited to using only email, can send an email that contains the command 'GET PRIMERS:SUBMISSION FORM' to the address netserv@ebi.ac.uk. The submission form will be sent as a response.
ACCURACY OF THE SEQUENCE
All sequences must be determined on both strands (or equivalent) and a statement to this effect must be included in the paper. Large sequences which contain short regions of sequence only determined on one strand may be accepted at the editors' discretion if they feel that there is a legitimate reason and that they do not compromise the results reported in the paper. The sequences in question should be clearly marked on the figure and the exact regions stated in the legend.
GENE NOMENCLATURE
Where applicable, all gene names must be in accordance to the officially approved gene symbols as described at:
SUBMISSION OF ANIMATION
Author-supplied animation related to articles accepted for publication will be included in the journal CD-ROM at no cost to authors. Animations are limited to a time duration of 30 seconds. Animation should be submitted to the journal editor with the final manuscript, after it has completed the refereeing process. Animation should be mentioned in the text. Indicate an approximate location for the animation call-out in the margin.
Animations in the following forms (in order of preference) can be accepted from authors:
-Video tape
-AVI or Quick Time files
-A sequence of still images
The following formats can be accepted:
-all uncompressed formats widely used on PC, Mac and UNIX
-JPEG for coloured and compressed images
-TIFF with a group IV compression for black and white compressed images
-FLI and FLC format from AutoDesk.
Authors who submit animations are requested to provide the following information:
-Video tape - format used
-AVI or QuickTime files - version used, and system used for disk file creation.
-Sequence of still images - format used, version and system used for disk file creation.
Authors who are unable to supply video tape, AVI or QuickTime files may provide the publisher with a set of sequential still images. Note that an animated sequence will consist of 13 to 15 still images per second of animation; e.g., if an animated sequence is 10 seconds in duration, it is made up of 130 images. Authors who are unable to submit in any of the above mentioned formats are advised to contact the publisher to discuss other options with the Publisher prior to submission.
PROOFS
Authors will receive page proofs (including figures) by air mail for correction, which must be returned to the typesetter within 48 hours of receipt. Please ensure that full postal address, including fax/email, is given on the first page of the typescript, so that proofs are not delayed in the post. Authors' alterations in excess of 10% of the original composition cost will be charged to authors.
REPRINTS
Twenty-five free reprints will be provided to the first-named author of each paper. Additional reprints may be ordered by completing the appropriate form sent with proofs.
PAGE CHARGES
There are no page charges to individuals or institutions. See journal inside cover for information on the Publisher's negative page charge voucher and voluntary page charge programs.
Editorial Board
Editor-in-Chief:
Stephan Beck - Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK
Editorial Board:
A. Bankier - MRC Laboratory of Molecular Biology, Cambridge, UK
M. Bishop - HGMP Resource Centre, Cambridge, UK
P. Bucher - Swiss Institute of Bioinformatics & Swiss Institute for Experimental Cancer Research, Epalinges, Switzerland
N. Bumstead - Institute for Animal Health, Compton, UK
M. Clark - British Antarctic Survey, Cambridge, UK
R. DeSalle - American Museum of Natural History, New York, NY, USA P.J. de Jong - Children's Hospital, Oakland Research Institute, Oakland, CA, USA
P. Denny - MRC UK Mouse Genome Centre and Mammalian Genetics Unit, Harwell, UK
R. DeSalle - American Museum of Natural History, New York, NY, USA
E. Eichler - Case Western Reserve University, Cleveland, OH, USA
T. Gibson - European Molecular Biology Laboratory, Heidelberg, Germany
I. Gut - Centre National de Genotype, Evry, France
T. Ikemura - National Institute of Genetics, Mishima, Japan
H. Inoko - Tokai University School of Medicine, Isehara, Japan
J. Kent - University of California, Santa Cruz, CA, USA
M. Kozak - Robert Wood Johnson Medical School, Piscataway, NJ, USA
J. Parkhill - Wellcome Trust Sanger Institute, Cambridge, UK
A. Rosenthal - Friedrich-Schiller Universit鋞, Berlin, Germany
L. Rowen - Institute for Systems Biology, Seattle, WA USA
L.M. Smith - University of Wisconsin, Madison, WI, USA
A. Volz - Institut f黵 Immungenetik, Berlin, Germany
S. Weissman - Boyer Centre for Molecular Medicine, New Haven, CT, USA
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