期刊名称：COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
Combinatorial Chemistry & High Throughput Screening publishes full length original research articles describing various topics in combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries) and/or high throughput screening (e.g. developmental, practical or theoretical). Ancillary subjects of key importance, such as robotics and informatics, will also be covered by the journal. In these respective subject areas, Combinatorial Chemistry & High Throughput Screening is intended to function as the most comprehensive and up-to-date medium available. The journal should be of value to individuals engaged in the process of drug discovery and development, in the settings of industry, academia, or government.
Instructions to Authors
Manuscript Submission: Manuscripts should be submitted to either the journal Editor or to one of the Regional Editors. The journal accepts the following types of contributions; Full length articles: should usually occupy six to ten printed pages (approximately 4000-7000 words); Full length reviews: should not occupy more than twenty-five printed pages; Mini reviews: should be up to ten printed pages in length; Communications: should occupy two to four pages (up to 3000 words). The manuscript, written in English should be typed in double spacing throughout on A4 or American quarto paper. Dot matrix print or any print that is difficult to read is unacceptable. Two copies of the manuscript must accompany the original, along with a computer disk, and should be sent to the Editor at his given address. All pages should be numbered. Abbreviations should be defined the first time that they are used in the manuscript and a list of abbreviations used should also be provided. Please supply your telephone and fax numbers and e-mail address with all submissions. All manuscripts submitted for publication will be subjected to peer-review and the turn-around time from submission to publication in the journal will be rapid.
Manuscript Organization: The manuscript should be divided as: Title page, abstract and the main text. The text may be subdivided further according to the areas to be discussed. This should be followed by the Acknowledgement (if any) and Reference sections. The first page should contain the title, the authors' names (initials and surname only), with an asterisk indicating the name of the principal author.
Abstract: The abstract should not exceed 250 words and it should condense the essential features of the article, with the focus on the major advances in the field.
Key Words: Authors must supply up to eight key words along with their manuscript.
Text: The main text should begin on a separate page and it may be subdivided into separate sections. Review articles should mention any previous important reviews in the field and contain a comprehensive discussion starting with the general background of the field. It should then go on to discuss the salient features of recent developments. The author should avoid presenting material which has already been published in a previous review. The reference numbers should be given in square brackets in the text. Acknowledgements should be kept to a minimum.
Tables:
* Data Tables should be submitted in Microsoft Excel or in Microsoft Word table format.
* Each table should include a title/caption explaining what the table shows. Detailed legends may then follow.
* Tables should be given on separate pages with indications on the left hand margin to the text, as to the appropriate placement of the tables.
* Tables should not contain vertical rules.
* Columns and rows of data should be made visibly distinct by ensuring the borders of each cell display as black lines.
* Tables should be numbered consecutively in order of their citation in the body of the text, with Arabic numerals.
* If a reference is cited in both the table and text, insert a lettered footnote in the table to refer to the numbered reference in the text.
* Tabular data provided as additional files can be submitted as an Excel spreadsheet.
Figures / Illustrations:
All authors must strictly follow the guidelines below for preparing illustrations for publication in Combinatorial Chemistry & High Throughput Screening.
Editorial Requirements:
The quality of the illustrations printed in the journal largely depends on the quality of the figures/illustration provided by the author. In preparing artwork or graphics for publication, keep in mind the following points.
* Submit the original artwork or a photographic print of the original for publication.
* Do not submit photocopies. (Hardcopy submission requirement)
* Illustrations should be provided as separate files, not embedded in the text. (Hardcopy submission requirement).
* Remove all color from graphics except for those illustrations (Greyscale), which are intended to be printed in color.
* Good quality of hardcopy originals are a requirement.
* Figures/illustrations cannot be modified or enhanced by the journal production staff.
* Figures should be referred to as “Fig. (1)”, “Fig. (2)” etc. in the text with figure numbers in bold within round bracket.
* Revised manuscripts should contain a complete set of artwork and photographs.
Technical Details:
* Figures should be provided on high quality, white, smooth opaque paper. (Hardcopy requirement)
Format & Resolution:
* The following file formats can be accepted. (Preference in order of appearance): PDF, TIFF, JPEG, GIF
* Illustrations must fit a single or double column format on the journal page, according to the following guideline below:
HEIGHT
WIDTH
SINGLE COLUMN
24 cm (max)
8.5 cm (max)
DOUBLE COLUMN
24 cm (max)
18 cm (max)
* Whenever possible, submit graphics that do not have to be reduced to fit the standard figure size.
* Use the best resolution available (hardcopy submission requirement). For online submission the maximum resolution is 300 dpi.
* Avoid textures and shadings giving a three-dimensional effect to the illustration.
* Symbols and lettering in the illustration should be of similar size.
* Smaller lettering is used.
* Font: Times New Roman or Helvetica is preferable. Font size: 10pt (maximum)
* Line drawings should have clear and sharp lines and should be of uniform density. Moreover, lines should be continuous without any breaks.
* Do not use lines thinner than 1 point.
Color Figures/Illustrations:
* Free colored artwork will only be published if the color is deemed scientifically necessary by the Editor-in-Chief.
* One color plate will be published free of charge in each article. The cost for the first additional published page of color figures is US$ 605; the second additional page will be for US$ 440, and each subsequent page for $ 303.
* Color figures should be supplied in CMYK not RGB colors.
* Required resolution for online submission is 300 dpi. In case of hardcopy submission, please use the maximum resolution available.
Photographs:
Submit high-contrast prints that are of single- or double-column width so that they will not have to be reduced when printed. Negatives are not acceptable. However, in case of hardcopy submission, color illustrations and plates can be published from 35 mm color slides.
Chemical Structures: Chemical structures must be prepared according to the guidelines below.
Structures should be prepared using a suitable drawing program e.g. ChemDraw and provided as separate file, submitted both on disk and in printed formats.
Numbers in bold should identify all chemical structure. If a name is also used to describe the compound, the associated number in bold should be in parenthesis, e.g. “compound (1)”.
Structure Drawing Preferences:
[As according to the ACS style sheet]
Drawing Settings:
Chain angle 120o
Bond spacing 18% of width
Fixed length 14.4 pt (0.500cm, 0.2in)
Bold width 2.0 pt (0.071cm, 0.0278in)
Line width 0.6 pt (0.021cm, 0.0084in)
Margin width 1.6 pt (0.096cm)
Harsh spacing 2.5 pt (0.088cm, 0.0347in)
Text settings:
Font Times New Roman / Helvetica
Size 10pt
Under the Preference Choose:
Units points
Tolerances 3 pixels
Under Page Setup Use:
Paper US letter
Scale 100%
References: For the format of references, see the ACS Style Guide, pp 106-114, examples:
Journal Reference: Barton, D.H.R.; Brewster, A.G.; Levy, S.V.; Rosenfield, M.N. J. Chem. Soc. Chem. Commun., 1977, 147, 2356.
Book Reference: Rahman, A.-U.; Shah, Z. Stereoselective Synthesis in Organic Chemistry, Springer-Verlag: New York, 1993.
Book Chapter Reference: Wheeler, D.M.S.; Wheeler, M.M. In Studies in Natural Products Chemistry; Atta-ur-Rahman, Ed.; Elsevier Science B. V: Amsterdam, 1994; Vol. 14, pp. 3-46.
Abstracts, unpublished data and personal communications (which can only be included if the permission has been obtained) should not be given in the reference section but they may be mentioned in the text with details provided as footnotes. All authors of referenced papers must be cited and there must be no use of the short hand version of et al. when citing the authors.
Manuscript Submission: Two copies of the manuscript must accompany the original along with the soft copy of the manuscript on a computer floppy disk(s) in MS Word file format (or created in any other well-known word processing software) should be submitted. To achieve rapid publication authors are encouraged to e-mail or fax their submission to the appropriate editorial office (see above) at the same time that they mail the manuscript. For even faster publication, authors are encouraged to submit their entire manuscript via Bentham’s online submission service (see below). Authors must provide their full address, telephone and Fax numbers with E-Mail address with all submissions.
For expedient and speedy reviewing of author's manuscripts, authors are strongly advised to include the PDF file of their manuscript on a floppy or zip disk, into the mailing material. At the same time the package is
Editorial Board
Koshi Arai (Taisho Pharmaceutical Co., Ltd., Saitama, JAPAN)
Ronald Frank (GBF, Braunschweig, GERMANY)
Ikuo Fujii (Biomolecular Engineering Research Institute, Osaka, JAPAN
Gunda I. Georg (University of Kansas, Lawrence, KS, USA)
Mario Geysen (GlaxoWellcome, Research Triangle Park, NC, USA)
David R. Goodlett (Proteomics Laboratory, Seattle, WA, USA)
Ole Hindsgaul (University of Alberta, Edmonton, Alberta, CANADA)
Victor J. Hruby (University of Arizona, Tucson, AZ, USA)
Kim D. Janda (Scripps Research Institute, La Jolla, CA. USA)
Daniel B. Kassel (Combichem, Inc. San Diego, CA, USA)
Donald Kyle (Purdue Pharma, L.P. Yonkers, NY, USA)
Brian Kay (Argonne National Laboratory, Argonne, IL, USA)
Kit S. Lam (University of Arizona, Tucson, AZ, USA)
Morten Meldal (Carlsberg Lab., Valby, DENMARK)
Lester A. Mitscher (University of Kansas, Lawrence, KS, USA)
Peter L. Myers (Libraria, Inc., San Jose, CA, USA)
Kyriacos C. Nicolaou (Scripps Research Institute, La Jolla, CA, USA)
Nobuyuki Okajima (Japan Tobacco, Inc., Osaka, JAPAN)
John M. Pezzuto ( Purdue University, West Lafayette, IN, USA)
J. Michael Ramsey (Oak Ridge National Lab., Oak Ridge, TN, USA)
Shigeki Sasaki (Kyushu University, Fukuoka, JAPAN)
Mark J. Suto (Neurion Pharmaceuticals, Pasadena, CA, USA)
Jun-ya Tamura (Yamanouchi Pharmaceutical Co., Ltd., Ibaraki, JAPAN)
Ronald N. Zuckermann (Chiron Corporation, Emeryville, CA, USA)
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