期刊名称:BIOSENSORS & BIOELECTRONICS
期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
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Biosensors & Bioelectronics is the principal international journal devoted to research, design, development and application of biosensors and bioelectronics. It is an interdisciplinary journal serving professionals with an interest in the exploitation of biological materials and designs in novel diagnostic and electronic devices including DNA chips, electronic noses and micro total analysis systems. Biosensors are defined as analytical devices incorporating a biological material (e.g. tissue, microorganisms, organelles, cell receptors, enzymes, antibodies, nucleic acids, natural products etc.), a biologically derived material (e.g. recombinant antibodies, engineered proteins, aptamers etc) or a biomimic (e.g. synthetic catalysts, combinatorial ligands, imprinted polymers) intimately associated with or integrated within a physicochemical transducer or transducing microsystem, which may be optical, electrochemical, thermometric, piezoelectric, magnetic or micromechanical. Biosensors usually yield a digital electronic signal which is proportional to the concentration of a specific analyte or group of analytes. While the signal may in principle be continuous, devices can be configured to yield single measurements to meet specific market requirements. Biosensors have been applied to a wide variety of analytical problems including in medicine, drug discovery, the environment, food, process industries, security and defence. The emerging field of Bioelectronics seeks to exploit biology in conjuction with electronics in a wider context encompassing, for example, biological fuel cells and biomaterials for information processing, information storage, electronic components and actuators. A key aspect is the interface between biological materials and electronics. While endeavouring to maintain coherence in the scope of the journal, the editors will accept reviews and papers of obvious relevance to the community, which describe important new concepts, underpin understanding of the field or provide important insights into the practical application and commercialisation of biosensors and bioelectronics.
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Instructions to Authors
Synthetic Receptors section The special section of Biosensors and Bioelectronics on Synthetic Receptors is dedicated to contributions focussing on the complementary intersection between synthetic receptors, nanotechnology, molecular recognition, molecular imprinting and supramolecular chemistry. Particular areas of science and applications covered by this section include:
- Design and study of molecular and supramolecular structures with molecular biorecognition and biomimetic properties
- Mechanistic investigation of the molecular recognition process in synthetic systems
- Development of a new generation of stable chimeric and biomimetic sensors for extreme environments, environmental and clinical monitoring
- The study of nanoelectronic elements with biorecognition/biomimetic signal transduction
- Identification and optimisation of new smart affinity separation matrices (adsorbents, membranes, capillaries, microchips) and separation processes based on synthetic receptors and smart materials
- Evaluation of new manufacturing procedures for large-scale production of synthetic receptors and for their integration with functional elements (adsorbents, sensors, bioreactors)
- Application of synthetic models of biochemical receptors in drug design
2. Types of contributions
- Full papers describing original research work not previously published, and these should not normally exceed 6800 words and 7 figures and /or tables;
- Short Communications - concise but complete descriptions of original limited investigations occupying a maximum of four printed pages (3400 words) with two figures and /or tables;
- Reviews- should cover part of the subject of active current interest. They may be submitted or invited.
- Book Reviews - should cover part of the subject of active current interest. They are by invite only.
3. Submission of contributionsSubmission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, without the written consent of the Publisher.
3.1 Online submission of contributions. Authors are encouraged to submit their paper online to one of the editors by using the Online Submission tool for Biosensors and Bioelectronics: at http://www.elsevier.com/locate/bios To submit online, authors are required to go to this website and upload their article (compuscript) and its associated artwork, an electronic (PDF) proof is generated and the reviewing process is carried out using that PDF. Authors submitting online are requested to send one exactly matching hard copy of new and revised submissions, to the editor by post. Full instructions on how to use the online submission tool and how to prepare your manuscript for online submission are available at the online submission website.
3.2 Submission of contributions on paper. Authors who prefer to submit their contribution in the conventional way (by post), should submit three copies of their manuscripts, one complete set of original illustrations and two copies to one of the Editors. For the final version, in addition to the original and two copies, authors should submit an electronic version of their manuscript on disk.
Papers should be sent to the editor-in-chief: Professor Anthony P F Turner, Cranfield University at Silsoe, Silsoe, Bedfordshire MK45 4DT, United Kingdom, Tel +44 (0)1525 863 005, Fax +44 (0)1525 863 360, E-mail: biosensors@cranfield.ac.uk
Papers for the Synthetic Receptors section should be sent to: Dr Chris Allender, Cardiff University, Welsh School of Pharmacy, Redwood Building, King Edward the VII Av., Cardiff CF1 3FX, UK. Tel +44 2920 875824, E-mail: allendercj@cf.ac.uk.
Authors are reminded that delays in publication may occur if the instructions for submission, disk and manuscript preparation are not strictly followed. Authors are strongly recommended to submit disks to aid rapid processing. To facilitate communication, authors are requested to provide their current e-mail address, telephone and fax number(s).
There are no page charges
4. Manuscript preparation
Manuscripts should be typed using double spacing on one side of consecutively numbered pages of A4 (21cm x 30 cm) or equivalent, with a wide margin on the left. In addition to the original, two copies should be submitted. When a revised version of a manuscript is submitted, a disk together with two copies of the manuscript including one set of high-quality original illustrations suitable for direct reproduction, should be submitted. A reply to the referee's comments should be included. Some flexibility of presentation will be allowed but authors are urged to arrange the subject matter clearly under such headings as Introduction, Materials & Methods, Results, Discussion, etc. For a rough estimate of the final length of their printed article, authors should count 850 words per full two-column page and four illustrations per page.
4.1. Language Papers will be published in English. Authors' manuscripts must be consistent in style, spelling and syntax. Authors in Japan please note that information about how to have the English of your paper checked, corrected and improved (before submission) is available from:
Elsevier Science K.K. Higashi Azabu 1-chome Building 4F 1-9-5 Higashi Azabu, Minato-ku Tokyo 106-0044 Japan
Tel: +81 (03) 5561-5032 Fax: +81 (03) 5561-5045
4.2. Title Articles should be headed by a concise but informative title. This should be followed by the name(s) of the author(s) and by the name and address of the laboratory in which the work was carried out. URL addresses may be included if desired. If the address of the author(s) at the time when the paper will appear is other than the laboratory in which the work was carried out this may be stated in a footnote, but footnotes should otherwise be avoided. The name and complete address of the person to whom the proofs should be sent must be given, inclusive of e-mail address, telephone and fax numbers, on a separate cover sheet. Recognition of financial support should not be made by a footnote to the title or name(s) of the author(s), but should be included in Acknowledgements at the end of the paper.
4.3. Abstracts The abstract is the part of your paper which will be read by the largest number of scientists so it plays a crucial role. The abstract is a condensation of the information (facts) in the paper; it is not a description of the contents of the paper. The abstract should present as much as possible of the qualitative and quantitative information contained in the paper yet it should be brief (50 - 250 words), specific and self-contained.
The abstract may include the following: 1. The context for the work; 2. The purpose or objectives of the work (what was the research question or problem and why it is important); 3. Theoretical or experimental methods used; 4. Results (qualitative and quantitative); 5. Conclusions and their limitations (what was the meaning of the results); 6. Safety information concerning dangerous compounds or procedures if relevant.
If the paper reports a new instrument or method then the abstract should include a description of its advantages and disadvantages compared to other established techniques. The abstract should not include trivial experimental details, references, figures or equations.
4.4. Keywords A maximum of six keywords should be given below the abstract to describe the contents of the paper.
4.5. Introduction A full-length submission should have a concise Introduction. This should state the reasons for the work, with references to previous work on the subject. It should not include the conclusions from the work being presented and should avoid extensive self-citation.
4.6. References References to published work should be indicated in the appropriate place in the text, according to the Harvard system (i.e. using author(s) name(s) and date), with a reference list, in alphabetical order, at the end of the paper. The list should give name(s) and initial(s) of author(s), year of publication and the exact title of the paper or book. For journals there should follow the title, volume number, and initial and final page numbers of article. For books there should follow the name(s) of the editor(s) (if appropriate), the name of the publisher and the town of publication. Where appropriate, initial and final page numbers should also be quoted. All references in this list should be indicated at some point in the text and vice-versa. Unpublished data or private communications should not appear in the reference list.
Journal article: Paivio, A., Jansen, Becker, L.J., 1975. Comparisons through the mind's eye. Cognition 37(2), 635-647.
Book: Strunk Jr., W., White, E.B., 1979. The Elements of Style, 3rd ed. MacMillan, New-York.
Edited Book: Letheridge, S., Cannon, C.R. (Eds.), 1980 Bilingual Education: Teaching English as a Second Language. Praeger, New-York.
Proceedings book: Chaddock, T.E., 1974. Gastric Emptying of a nutritionally balanced liquid diet. In: Daniel. E.E. (Ed.), The Interactional View. Norton, New-York, pp. 71-87 (reprint from Acta Psiquiatrica Psicologica de America Latin 11, 321-330 (1965)).
4.7. Tables Tables should be typed in double spacing on separate sheets and provided with a suitable heading. Tables should be clearly referred to in the text using Arabic numerals. Considerable thought should be given to layout so that the significance of the results can be easily grasped. Each table should have a title which makes the general meaning understandable without reference to the text. Vertical lines should not be used to separate columns. Column headings should be sufficiently explanatory, and presented in a way consistent with the column width. Columns of figures multiplied by the same power of ten should not be presented as such. The power of ten should be indicated in the column heading, e.g.: 104[NaCl]/mol l- 1 4.2 3.5 0.26 rather than [NaCl]/mol l-1 4.2 x 10-4 3.5 x 10- 4 2.6 x 10-5
4.8. Illustrations Do not import the figures into the text file when submitting your paper on disk. Instead indicate the approximate locations of the illustrations directly in the elctronic text and on the manuscript. Supply high-quality printouts on white paper produced with black ink. The lettering and symbols, as well as other details, should have proportionate dimensions, so as not to become illegible or unclear after possible reduction; in general, the figures should be designed for a reduction factor of two to three. The degree of reduction will be determined by the Publisher. Illustrations will not be enlarged. Consider the page format of the journal when designing the illustrations. Photocopies are not suitable for reproduction. Do not use any type of shading on computer-generated illustrations. Please supply original photographs for reproduction, printed on glossy paper, very sharp and with good contrast. Remove non-essential areas of a photograph. Do not mount photographs unless they form part of a composite figure. Where necessary, insert a scale bar in the illustration (not below it), as opposed to giving a magnification factor in the legend. Note that photocopies of photographs are not acceptable. Submit colour illustrations as original photographs, high-quality computer prints or transparencies, close to the size expected in publication, or as 35 mm slides. Polaroid colour prints are not suitable. Further information concerning colour illustrations and costs is available from the Publisher.
The axes of a graph should be clearly labelled with the quantity plotted, and its units. Positive values should be plotted upwards and to the right.
A photocopy of each figure should also be supplied with each copy of the manuscript. They should be numbered and identified with the names of the authors. Original illustrations are not returned except upon special request.
4.9. Further information For enquiries relating to the submission of articles (Including electronic submission where available) please visit the Author Gateway from Elsevier Science Author Gateway. The author gateway also provides the facility to track accepted articles and set up e-mail alerts to inform you of when an article's status has changed, as well as detailed artwork guidelines, copyright information, frequently asked questions and more. Contact details for questions arising after acceptance of an article, especially those relating to proofs, are provided when an article is accepted for production.
5. Preparation of manuscripts on disk
5.1. Main Text Articles prepared using any of the more popular word-processing packages are acceptable but Word, Word Perfect or Latex is prefered. Please note the following points.
- Submissions should be made on a double-density or high-density 3.5" diskette, zip disk or CD (either MS-DOS or Macintosh).
- The disk format, wordprocessor format, file name(s) and the title and author(s) of the article must be indicated on the diskette.
- The disk must always be accompanied by a hard-copy version of the article, and the content of the two must be identical.
- The disk text must be the same as that of the final refereed, revised manuscript.
- The article must be saved in the native format of the word processor used, e.g. WordPerfect, Microsoft Word, etc.
- Although most popular word processor file formats are acceptable, we cannot guarantee the usability of all formats. If the disk you send us proves to be unusable, we will publish your article from the hard copy.
- Please do not send ASCII files as relevant data may be lost.
- The text should be in single-column format. Keep the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. In particular, do not use the wordprocessor's options to justify text or to hyphenate words. However, do use bold face, italics, subscripts, superscripts etc.
- Do not embed 'graphically designed' equations or tables, but prepare these using the wordprocessor's facility. When preparing tables, if you are using a table grid, use only one grid for each individual table and not a grid for each row. If no grid is used, use tabs, not spaces, to align columns.
- Leave a blank line between each paragraph and between each entry in the list of bibliographic references.
- Tables should preferably be placed in the same electronic file as the text. Authors should consult a recent issue of the Journal for table layout.
More information about submitting your manuscript on disk can be found at http://www.elsevier.com/locate/disksub
5.2. Graphics General submitting your artwork in an electronic format helps us to provide your work to the best possible standards ensuring accuracy, clarity and a high level of detail.
Requirements
- Always supply high-quality printouts of your artwork, in case conversion of the electronic artwork is problematic.
- Make sure you use uniform lettering and sizing of your original artwork.
- Save text in illustrations as "graphics" or enclose the font.
- Number the illustrations according to their sequence in the text.
- Use a logical naming convention for your artwork files, and supply a separate listing of the files and the software used.
- Provide all illustrations as separate files and as hardcopy printouts on separate sheets.
- Provide captions to illustrations separately.
- Produce images near to the desired size of the printed version.
Files can be stored on 3? inch diskette, ZIP-disk or CD (either MS-DOS or Macintosh). A detailed guide on electronic artwork is available on our website: http://www.elsevier.com/locate/authorartwork/ You are urged to visit this site; some excerpts from the detailed information are given here. Formats
Suggested drawing/image applications for your graphics are Adobe PhotoShop, Adobe Illustrator, CorelDraw and Freehand. (Note the resolution requirements for line drawings, halftones, and line/halftone combinations as given below.) If you are using other applications, please convert the drawing or graphic images to one of the following formats:
EPS: Vector drawings. Embed the font. TIFF: Colour or greyscale photographs (halftones): always use 300 dpi. For colour images always use CMYK. TIFF:Bitmapped line drawings: use 1000 dpi. TIFF:Combinations bitmapped line/half-tone: a minimum of 500 dpi is required.
Scan your colour illustrations at 300 dpi (500 dpi for colour line/halftone combinations). With CMYK electronic files include a 4-colour machine or cromalin proof and check that all the separations (if provided) are colour-coded. Produce computer-generated graphics in greyscale if they are to be published in black and white. Please do not:
- Supply embedded graphics in your wordprocessor (spreadsheet, presentation) document;
- Supply files that are optimised for screen use (like GIF, BMP, PICT, WPG); the resolution is too low;
- Supply files that are too low in resolution;
- Submit graphics that are disproportionately large for the content.
6. Symbols and terminology
6.1. General It is strongly preferred that authors follow the recommendations of the IUPAC Manual of Symbols and Terminology for Physico-chemical Quantities and Units, edited by I.M. Mills, Blackwells, Oxford, 1988. Some examples of recommended usage are given here.
If authors depart from these recommendations, articles may be returned for correction or corrected in the Editorial Office. In the latter case, no responsibility for errors can be assumed. S.I. units should be used. "Equivalents" and "Normalities" should not be used. Meaningless units (e.g. e.u.) should not be used. Concentration should be denoted by the chemical formula in square brackets, or by lowercase c. Units of concentration should be given as mol dm-3, mol cm-3, M, mol l-1, etc. Mixtures should be indicated by a plus sign, e.g. Zn + Cu, H2O + CH3OH etc. Interfaces should be indicated by a vertical bar (see equations (1) and (2) below.) The function G should be called Gibbs energy, not Gibbs free energy or free enthalpy. Some terms of historical interest only should be avoided, e.g. depolarizer, polarization (of electrodes).
6.2. Mathematical formulae Formulae should be typewritten, if possible.
Subscripts and superscripts should be set off clearly. Special care should be taken, if a dot-matrix printer is used, that subscripts and superscripts are legible. Greek letters and handwritten symbols should be explained in the margin where they are first used. Special care should be taken to show clearly the difference between zero (0) and the letter O, and between one (1) and the letter l. The meaning of all symbols should be given immediately after the equation in which they are first used, or a list of definitions provided. Abbreviations not in common use should be defined. For fractions, especially in the text, space can be saved by using the solidus (/) or by using negative exponents instead of a horizontal line, e.g. Ip/2m or Ip(2m)-1 rather than Ip 2m If necessary, parentheses can be used to avoid ambiguity. All equations (mathematical and chemical) should be numbered sequentially in parentheses in the right-hand margin. They should be treated as part of the text. The use of fractional powers instead of root signs is recommended. Complicated powers of e are often more conveniently denoted by exp(...). Natural or Napierian logarithms should be denoted by ln, whereas decadic logarithms should be denoted by log. The multiplication sign should be used in floating point numbers to avoid confusion, e.g. 4.25 x 105. The decimal point should always be denoted by a full stop.
6.3. Chemical formulae and nomenclature Nomenclature should follow IUPAC recommendations. For inorganic chemistry, see: Nomenclature of Inorganic Chemistry, Butterworths, London, 1971. For organic chemistry, see: Nomenclature of Organic Chemistry, Pergamon, Oxford, 1979. Structural formulae should be numbered with roman numerals: they should be submitted on separate sheets in a form suitable for direct reproduction. Drawn structural formulae should use upright lettering.
7. Proofs
The corresponding author will receive a proof in PDF format by Email, which he/she is requested to correct and return as soon as possible, preferably by fax. No new material may be inserted in the text at the time of proofreading. Any Note added in proof must be dated and the author must have requested and received the Editor's approval.
8. Copyright
Upon acceptance of an article, authors will be asked to transfer copyright. This transfer will ensure the widest possible dissemination of information. A letter will be sent to t
Editorial Board
Editor-in-Chief:
A.P.F. Turner, Cranfield University at Silsoe, Silsoe, Bedfordshire MK45 4DT, UK
Editorial Assistant
Alice X. J. Tang, Editorial Assistant to Professor A.P.F. Turner, Cranfield University at Silsoe, Silsoe, Bedfordshire MK45 4DT, UK
Regional Editor for N & S America:
F.S. Ligler, Center for Bio/Molecular Science and Engineering, Code 6900, Naval Research Laboratory, Washington, DC 20375-5348, USA
Regional Editor for Asia-Pacific Region:
E. Tamiya, Japan Advanced Institute of Science and Technology, School of Materials Sciences, 1-1 Asahidai, Yatsunokuchi, Ishikawa 923-1292, Japan
Editor Synthetic Receptors section:
C. Allender, Cardiff University, Welsh School of Pharmacy, Redwood Building, King Edward the VII Av., Cardiff CF1 3FX, UK Email: allendercj@cf.ac.uk.
Editorial Board:
A.E.G. Cass, London, UK L.C. Clark Jnr, Yellow Springs, OH, USA J. Cooper, Glasgow, UK D. Cullen, Silsoe, Bedfordshire, UK B. Danielsson, Lund, Sweden S. Dong, Jilin, China L. Gorton, Lund, Sweden E.A.H. Hall, Cambridge, UK W. Heineman, Cincinnati, OH, USA I.J. Higgins, Beds, UK J. Homola, Prague, Czech Republic J. Janata, Atlanta, GA, USA I. Karube, Tokyo, Japan P.T. Kissinger, Lafayette, IN, USA J. Kulys, Vilnius, Lithuania M. Mascini, Florence, Italy B. Mattiasson, Lund, Sweden C. McNeil, Newcastle-upon-Tyne, UK M.E. Meyerhoff, University of Michigan, Ann Arbor, USA J.C. Pickup, London, UK R. Renneberg, Hong Kong University, China F. Scheller, Golm, Germany J.S. Schultz, Pittsburgh, PA, USA W.R. Seitz, Durham, NH, USA K. Sode, Tokyo, Japan D. Thomas, Compiegne, France M. Thompson, Toronto, Ontario, Canada Y. Umezawa, Sapporo, Japan H. Vogel, Lausanne, Switzerland G. Whitesides, Cambridge, MS, USA R.M. Wightman, Chapel Hill, NC, USA G.S. Wilson, Lawrence, KS, USA Y. Yevdokimov, Moscow, Russia
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