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期刊名称：BIOMATERIALS ISSN： 0142-9612 版本： SCI-CDE 出版频率： Semimonthly 出版社： ELSEVIER SCI LTD, THE BOULEVARD,LANGFORD LANE,KIDLINGTON, OXFORD, ENGLAND, OX5 1GB   出版社网址： http://www.elsevier.nl/ 期刊网址： http://www.elsevier.nl/inca/publications/store/3/0/3/9/2/index.htt 影响因子： 6.6469(2008) 主题范畴： ENGINEERING, BIOMEDICAL;    MATERIALS SCIENCE, BIOMATERIALS;    CELL & TISSUE ENGINEERING 期刊简介(About the journal)    投稿须知(Instructions to Authors)    编辑部信息(Editorial Board)    About the journal   Biomaterials is an international journal covering the science and application of biomaterials and associated medical devices. It is the aim of the journal to provide a peer-reviewed forum for the publication of original papers and authoritative review papers dealing with the most important issues facing the use of materials in clinical practice. The scope of the journal covers the basic science and engineering aspects of biomaterials, including their mechanical, physical, chemical and biological properties, relevant design and production characteristics of devices constructed of these materials, and their clinical performance. In this context, biomaterials are defined as all those materials used in medical devices in which contact with the tissues of the patient is an important and guiding feature of their use and performance. They include a range of metals and alloys, glasses and ceramics, natural synthetics, polymers, biomimetics, composites and natural or tissue-derived materials, including combinations of synthetic materials and living tissue components. The journal is relevant to all applications of biomaterials including implantable medical devices, tissue engineering and drug delivery systems.     Instructions to Authors   Effective 1st June 2003, Biomaterials has moved to a web-based submission and review system. As of this date, email and hard copy have ceased to be acceptable modes of submission. Editorial Manager is an web-based submission and review system. Authors may submit manuscripts and track their progress through the system to publication. Reviewers can download manuscripts and submit their opinions to the editor. Editors can manage the whole submission/review/revise/publish process. Please register at: http://biomat.edmgr.com Referees, whose names are not normally disclosed to the authors, will study all contributions which the Editor-in-Chief deems to be of sufficient significance and interest to be sent for peer review. The criteria by which this initial assessment is made include relevance to the scope of the journal, the originality of the work and its significance to the broad development of the field of biomaterials. Author Agreement In addition to uploading manuscripts and figures, it is imperative that the corresponding author of each manuscript uploads a separate "Author Agreement". The author agreement must unambiguoulsy state that that the paper being submitted: 1. Is original. 2. Has been written by the stated authors who are ALL aware of its content and approve its submission. 3. Has not been published previously. 4. Is not under consideration for publication elsewhere. 5. If accepted will not be published elsewhere in the same form, in any language, without the written consent of the publisher. NB The Author Agreement is independant of, and in addition to, the "Transfer of Copyright" agreement which is issued on acceptance. Amendments to Manuscripts In order to maintain the integrity of the scientific record, the version that is published in an issue on ScienceDirect and in print MUST be identical. One set of page proofs will be sent to the corresponding author, to be checked for typesetting/editing errors. Proofs are NOT to be considered as drafts. No changes in, or additions to, the accepted (and subsequently edited) manuscript will be allowed at this stage. Proofreading is solely the responsibility of the corresponding author. Manuscript Preparation General: Manuscripts must be word processed (preferably in Word format), double-spaced with wide margins and a font size of 12 or 10 pt. Please check the current style of the journal, particularly the reference style (Vancouver), and avoid excessive layout styling as most formatting codes will be removed or replaced during the processing of your article. In addition, do not use options such as automatic word breaking, justified layout, double columns or automatic paragraph numbering (especially for numbered references). However do use bold face, italic, subscripts, superscripts etc. The corresponding author should be identified (include a Fax number and E-mail address). Full postal addresses must be given for all co-authors. The Editors reserve the right to adjust style to certain standards of uniformity. The preferred style is: Surname, Initials, Department, Institution, City/State, Postal Code, Country. Authors should retain copies of all versions of their manuscript submitted to the journal. Authors are especially requested to be vigilant over the submission of the correct version of the manuscript at the various stages of the editorial process. Paper Length: Authors are urged to write as concisely as possible. Abstracts: All manuscripts are to be supplied with an Abstract of about 100-200 words in length, with 4-6 keywords. A keyword list can be found at the end of these instructions (click here). Text: Follow this order when typing manuscripts: Title, Authors, Affiliations, Abstract, Keywords, Main text, Acknowledgements, Appendix, References, Figure Captions and then Tables. Do not import the Figures or Tables into your text. The corresponding author should be identified with an asterisk and footnote. All other footnotes (except for table footnotes) should be identified with superscript Arabic numbers. An abbreviated title for use as a running headline should also be supplied. Authors are requested to acknowledge funding sources for the work. Units: The SI system should be used for all scientific and laboratory data; if, in certain instances, it is necessary to quote other units, these should be added in parentheses. Temperatures should be given in degrees Celsius. The unit 'billion' (109 in America, 1012 in Europe) is ambiguous and must not be used. If a large number of symbols are used it is helpful if authors submit a list of these symbols and their meanings. References: All publications cited in the text should be presented in a list of references following the text of the manuscript. In the text refer to references by a number in square brackets on the line (e.g. Since Peterson[1]), and the full reference should be given in a numerical list at the end of the paper. References should be given in the following form, which is designated Vancouver : 1. Driessens FCM, Boltong MG, Bermudez O, Planell JA. Formulation and setting times of some calcium orthophosphate cements: a pilot study. J Mater Sci: Mater Med 1993;4:503-508. 2. Nancollas H. In vitro studies of calcium phosphate crystallisation. In: Mann S, Webb J, Williams RJP, editors. Biomineralization. Chemical and biochemical perspectives. New York: VCH, 1989. p. 157-182. 3. Brown W, Chow LC. Combinations of sparingly soluble calcium phosphates in slurries and paste as mineralizers and cements. US Patent No. 4612053, 1986. Illustration Preparation In the initial submission and review stage, authors are required to provide electronic versions of their illustrations. When an article has been accepted, authors must be prepared to provide all illustrations in electronic and camera-ready format, (suitable for reproduction, which may include reduction, without retouching). General: Information relating to the preferred formats for Artwork and Illustrations may be found at http://authors.elsevier.com. Photographs, charts and diagrams are all to be referred to as "Figure(s)" and should be numbered consecutively in the order to which they are referred. They should accompany the manuscript, but should not be included within the text. All hard copy illustrations should be clearly marked on the back with the figure number and the author's name. All figures are to have a caption. Captions should be supplied on a separate sheet. Line drawings: All lettering, graph lines and points on graphs should be sufficiently large and bold to permit reproduction when the diagram has been reduced to a size suitable for inclusion in the journal. Dye-line prints or photocopies are not suitable for reproduction. Do not use any type of shading on computer-generated illustrations. Photographs: Original photographs must be supplied as they are to be reproduced (e.g. black and white or colour). If necessary, a scale should be marked on the photograph. Please note that photocopies of photographs are not acceptable. Colour: It is rarely necessary to produce art-work, including graphs and line drawings, in colour. Certain illustrations (e.g. micrographs showing multiple stains) will be approved for publication in colour but only if, in the opinion of the Editors, the figures convey information not apparent in monochrome. Authors will normally be expected to bear the additional cost of colour printing, although where funding cannot be obtained, a limited number of bursaries are available at the Editor's discretion. Please note that if figures are supplied in colour, they will automatically be available online in colour at no extra charge, even if the print version is monochrome. Tables: Tables should be numbered consecutively and given a suitable caption and each table typed on a separate sheet. Footnotes to tables should be typed below the table and should be referred to by superscript lowercase letters. No vertical rules should be used. Tables should not duplicate results presented elsewhere in the manuscript, (e.g. in graphs). Acceptance After acceptance, authors may be requested to provide Elsevier with hard-copy and electronic versions of their manuscript and their figures. The electronic copy, on floppy disk, CD-ROM or ZIP, should match the hardcopy exactly, therefore always keep a backup copy of the electronic file for reference and safety. Full details of electronic submission and formats can be obtained from http://authors.elsevier.com . Always keep a backup copy of the electronic file for reference and safety. Full details of electronic submission and formats can be obtained from http://authors.elsevier.com Track a Paper Authors can now track their paper status online after the paper has been accepted and forwarded to the Publisher. Enter your Elsevier reference number (JBMT xxx) and the Corresponding author's family name at the following web page: http://authors.elsevier.com/trackpaper.html. Corresponding authors will receive an acknowledgement email from Elsevier with the reference number and the family name on it. Authors can also go to the 'track a paper' page by clicking onto the 'track a paper' button on the left hand side of the journal home page. Proofs Proofs will be sent to the author (first named author if no corresponding author is identified of multi-authored papers) and should be returned within 48 hours of receipt. Corrections should be restricted to typesetting errors; any others may be charged to the author. Any queries should be answered in full. Please note that authors are urged to check their proofs carefully before return, since the inclusion of late corrections cannot be guaranteed. Proofs are to be returned to Elsevier Science Log-in Department as soon as possible by e-mail, fax, courier, or airmail. The fax number and office address for courier services will be included with your proofs. Offprints Twenty-five offprints will be supplied free of charge. Further offprints can be ordered at a specially reduced rate using the order form sent to the corresponding author after the manuscript has been accepted. Orders for reprints will incur a 50% surcharge. Copyright All authors must sign the "Transfer of Copyright" agreement before the article can be published. This transfer agreement enables Elsevier Science Ltd to protect the copyrighted material for the authors, but does not relinquish the author's proprietary rights. The copyright transfer covers the exclusive rights to reproduce and distribute the article, including reprints, photographic reproductions, microfilm or any other reproductions of similar nature and translations. It also includes the right to adapt the article for use in conjunction with computer systems and programs, including reproduction or publication in machine-readable form and incorporation in retrieval systems. Authors are responsible for obtaining from the copyright holder permission to reproduce any figures for which copyright exists. Author Enquiries For enquiries relating to the status of accepted manuscripts through our online Tracking Feature, author Frequently Asked Questions and any other enquiries relating to Elsevier Science, please consult the Author Gateway http://authors.elsevier.com. For specific enquires on the preparation of electronic artwork and text, consult the Quick Guide on the right hand margin of the Author Gateway http://authors.elsevier.com. Contact details for questions arising after acceptance of an article, especially those relating to proofs, are provided when an article is accepted for publication. Keyword List Back to Instructions A Abdomen Abrasion Absorption Acid phosphatase Acrylic acid Acrylics Actin Activated charcoal Activation energy Adenovirus Adhesion Adhesion mechanism Adhesion molecule Adipose tissue engineering Adsorption AFM (atomic force microscopy) Affinity Age / ageing Albumin Alginate Alkaline phosphatase Allergy Allogeneic cell Alumina Aluminium Ames test Amino acid Aneurysm Angiogenesis Animal model Anodic phenomena Anti-adhesion Antibacterial Anticoagulant Antigenicity Antimicrobial Antioxidant Antisense Apatite structure Apolipoprotein Apoptosis Aragonite Arterial structure Arterial tissue engineering Arthritis Arthroplasty Astrocyte Audiology Autoimmunity Autologous cell B Bacteria Bacterial adhesion Bioabsorption Bioactive glass Bioactivity Bioartificial liver Bioartificial pancreas Biocompatibility Biodegradation Bioerosion Biofilm Biomimetic material Biomineralisation Bioprosthesis Bioreactor Bioresorption Biosensor Bis-phenol A derivative Bladder Bladder tissue engineering Blood Blood compatibility Blood flow BMP (bone morphogenetic protein) Bone Bone cement Bone graft Bone healing Bone ingrowth Bone marrow Bone regeneration Bone remodelling Bone repair Bone tissue engineering Brain Brittleness Brushite Burn C Calcification Calcite Calcium Calcium carbonate Calcium phosphate Calcium phosphate cement Calcium phosphate coating Carbon Carcinogenesis Cardiac rhythm Cardiac tissue engineering Cardiomyocyte Cartilage Cartilage tissue engineering Casting Catheter Catheter infection Cell activation Cell adhesion Cell culture Cell encapsulation Cell morphology Cell proliferation Cell signalling Cell spreading Cell viability Cellulose Ceramic structure Chemiluminescence Chemotaxis Chemotherapy Chinese herbal medicine Chitin / chitosan Chondrocyte Chondroitin sulphate Clotting Coagulation Cobalt alloy Co-culture Collagen Collagen structure Complement Compliance Composite Compression Computational fluid dynamics Confocal microscopy Connective tissue Constitutive modelling Contact angle Contact lens Contact phase activation Controlled drug release Copolymer Copper Cornea Corrosion Corrosion product Coupling agent Crack Creep Crevice corrosion Cross-linking Crystal growth Crystallinity Crystallisation Crystallography Cyclooxygenase Cytokine Cytotoxicity D Degradation Demineralisation Dendrimer Dental adhesive Dental alloy Dental amalgam Dental cement Dental implant Dental restorative material Dentine Dentine bonding agent Dermis Dextran Diabetes Dialysis Diamond Dielectric constant DMA (dynamic mechanical analysis) DNA Drug delivery Drug release DSC (differential scanning calorimetry) Dura E ECM (extracellular matrix) Elasticity Elastin Elastomer Electrical stimulation Electroactive polymer Electrochemistry Electrode Electron beam Electron microscopy Electronic material Electrophysiology ELISA Ellipsometry Embolisation Endodontics Endothelial cell Endothelialisation Endothelium Endotoxin ENT surgery Enzyme Epithelial cell Epithelium ESCA (electron spectroscopy for chemical analysis) Esterase Extracorporeal circulation Extrusion F FACS (fluorescence activated cell sorting) Fatigue Ferroelectrics Fibrin Fibrinogen Fibroblast Fibroblast growth factor Fibronectin Fibrosis Fibrous tissue Finite element analysis Flow cytometry Fluorine - fluoride Fluorescence Fluorocarbon Foreign body giant cell Foreign body response Fractal Fracture mechanism Fracture toughness Free form fabrication Free radical Fretting Friction FTIR Fungal infection G Gamma irradiation Gelatin Gene expression Gene therapy Gene transfer Genetic engineering Genotoxicity Glass Glass ceramic Glass ionomer Glass transition temperature Glaucoma Glycosaminoglycan Gold Growth factors H Haemocompatibility Haemodialysis Haemolysis Haemostasis Hair follicle Heart Heart assist Heart valve Heparin Hepatocyte Hip replacement prosthesis Histomorphometry Hyaluronic acid / hyaluronan Hydrogel Hydrolysis Hydrophilicity Hydrophobin Hydroxyapatite Hydroxyapatite coating Hydroxyapatite composite Hydroxyapatite - drug Hydroxyethylmethacrlate Hydroxyproline Hypersensitivity I Image analysis Immune response Immunochemistry Immunomodulation Immunostimulation In situ hybridisation In vitro test In vivo test Infection Inflammation Infrared spectrum Integrin Interface Interleukin Intervertebral disc Intimal hyperplasia Intraocular lens Intravascular stent IPN (Interpenetrating polymer network) Ion beam Ion implantation Iridium Islet J Joint replacement K Keratin Keratinocyte Keratoprosthesis Knee replacement L Laminin Langmuir Blodgett film Laser Laser ablation Laser manufacturing Latex Leukocyte Ligament Ligament prosthesis Lipase Lipid Liposome Liquid crystal Liver Liver perfusion Lung Lymphocyte Lymphokine Lysozyme M Macrophage Magnesium Magnetism Matrix metalloproteinase Mechanical properties Mechanical test Membrane Mercury Mesenchcymal stem cell Metal ion Metal ion release Metal ion toxicity Metal - ceramic bonding Metal surface treatment Metallography Metalloproteinase Micelle Microbiology Microcapsule Microencapsulation Micromachining Micromotion Micropatterning Microsphere Microstructure Microwave Middle ear Modelling Molecular biology Molecular imaging Molecular modelling Molecular weight Monocyte Monomer MRI (magnetic resonance imaging) mRNA MTT assay Mucosa Mucosal adhesion Muscle Mutagenicity N Nacre Nanocomposite Nanoindentation Nanoparticle Nanotopography Neointima Nerve Nerve growth factor Nerve guide Nerve regeneration Nerve tissue engineering Neural cell Neural network Neural prosthesis Neutrophil Nickel Nickel-titanium alloy Nitinol Nitric oxide Non-woven fabric O Ophthalmology Organ culture Orthodontics Osseointegration Osteoblast Osteoclast Osteoconduction Osteogenesis Osteolysis Osteopontin Osteoporosis Oxidation Oxygen permeation Oxygenation P Pacemaker Palladium Pancreas Particulates Passivation Pathology PCR (polymerase chain reaction) Peptide Percutaneous implant Periodontium Peritoneum Phospholipid Phosphorylcholine Photolithography Photopolymerisation Photosensitisation Phthalate Pitting Plasma Plasma polymerisation Plasma proteins Plasma spraying Plasminogen Plasticisation Plasticity Platelet Platelet activation Platelet adhesion Platinum Pluronics Polyacrylic acid Polyacrylonitrile Polyamino acid Polyanhydride Polycaprolactone Polycarbonate Polydioxanone Polydimethylsiloxane Polyetheretherketone Polyethylene Polyethylene oxide Polyethylene terephthalate Polyglycolic acid PolyHEMA Polyhydroxybutyric acid Polylactic acid Polymerisation Polymethylmethacrylate Polyorthoester Polypropylene Polysaccharide Polysulphone Polytetrafluoroethylene Polyurethane Polyvinylalcohol Polyvinylchloride Porcine tissue Porosity Primitive cell Progenitor cell Protein Protein adsorption R Radiopacity Rapid prototyping Recombinant protein Reproductive toxicity Restenosis Retina RGD peptide S SBF (simulated body fluids) Scaffold Schwann cell Selectin Self assembly SEM (scanning electron microscopy) Shape memory Shear Signal transducing mediator Silane Silica Silicate Silicon Silicon carbide Silicon nitride Silicone Silicone fluid Silicone gel Silicone elastomer Silk Siloxane Silver SIMS (secondary ion mass spectroscopy) SIS (small intestine submucosa) Smooth muscle cell Soft tissue biomechanics Sol-gel techniques) Spinal surgery Stainless steel Starch Steel Stem cell Stent Sterilisation Strain rate Stress analysis Stress cracking Sulphonated polymer Superelasticity Superoxide Surface analysis Surface energy Surface grafting Surface modification Surface roughness Surface texture Surface topography Surface treatment Surgical mesh Suture Swelling T Tantalum TEM (transmission electron microscopy) Tendon Tendon prosthesis Tension TGF (transforming growth factor) Thermally responsive material Thiol Three dimensional printing Thrombin Thrombogenicity Thrombomodulin Thrombosis Tissue adhesive Tissue plasminogen activator Titanium Titanium alloy Titanium oxide Tracheal prosthesis Transplantation U Urinary tract V Vascular grafts Vinculin Viscoelasticity VWF (von Willibrand factor) W Wear debris Wear mechanism Wettability Wollastonite Wound closure Wound dressing Wound healing X Xenotransplantation Xerogel XRD (x-ray diffraction) XPS (x-ray photoelectron spectroscopy) Z Zinc Zirconia   Editorial Board   Editor-in-Chief: D.F. Williams, Department of Clinical Engineering, University of Liverpool, Duncan Building, Royal Liverpool University Hospital, Liverpool L69 3BX, UK Special Issues Editor: T. Mikos, Rice University, Houston, USA Associate Editors: B. Boyan, Georgia Institute of Technology, USA G. Ciapetti, Istituti Ortopedici Rizzoli, Italy P. Ducheyne, University of Pennsylvania, USA D.W. Grainger, Colorado State University, CO, USA J.A. Hubbell, Institute for Biomedical Engineering, Zurich, Switzerland J. Hunt, University of Liverpool, UK C.J. Kirkpatrick, Johannes Gutenberg University, Mainz, Germany H.A. McKellop, Orthopaedic Hospital and the University of California, Los Angeles, USA C. van Blitterswijk, IsoTis BV, The Netherlands P. Zilla, University of Cape Town, South Africa International Editorial Board: J. Anderson, Case Western University, Cleveland, USA K. Anselme, University of Littoral, France M.A. Barbosa, University of Porto, Portugal L. Brannon-Peppas, University of Texas at Austin, Texas, USA J.L. Brash, McMaster University, Hamilton, Canada T. Chirila, University of Western Australia, Australia S. Cooper, North Carolina State University, USA E.R. Edelman, Massachusetts Institute of Technology, Cambridge, USA L. Griffith, Massachusetts Institute of Technology, USA D.W. Grijpma, University of Twente, The Netherlands G. Gronowicz, University of Connecticut Health Center, USA U. Gross, Free University Berlin, Germany E. Ingham, University of Leeds, UK A. Jayakrishnan, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum, India W.H. de Jong, National Institute of Public Health and Environment, The Netherlands E. Khor, National University of Singapore, Singapore Y.H. Kim, Korea Institute of Science and Technology, Seoul, Korea J. Kohn, Rutgers University, Piscataway, USA T. Kokubo, Kyoto University, Japan J. Kopecek, University of Utah, Salt Lake City, USA J. Kost, Sontra Medical, USA D.A. Lauffenburger, Massachusetts Institute of Technology, Cambridge, USA C. Laurencin, University of Virginia, USA K.W. Leong, Johns Hopkins University, Baltimore, MD, USA R.J. Levy, The Children's Hospital of Philadelphia, PA, USA E. Mathiowitz, Brown University, Providence, USA J-M. Meyer, University of Geneva, Switzerland C. Migliaresi, University of Trento, Italy B.K. Milthorpe, University of New South Wales, Kensington, Australia N.A. Peppas, University of Texas, Austin, USA R.M. Pilliar, University of Toronto, Canada B. Ratner, University of Washington, Seattle, USA M. Saltzman, Cornell University, New Haven, USA K. Smetana, Charles University, Prague, Czech Republic P. Stayton, University of Washington, USA M. Textor, Swiss Federal Institute of Technology, USA P. Thomsen, University of G鰐eborg, Sweden D. Tirrell, California Institute of Technology,USA M.J. Yaszemski, Mayo Clinic, USA