期刊名称：STEM CELL REPORTS
 期刊简介(About the journal)
投稿须知(Instructions to Authors)
编辑部信息(Editorial Board)
About the journal
Stem Cell Reports is an open access forum communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on shorter, single-point manuscripts that report original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians.
Given the rapidly increasing impact of stem cell research to regenerative medicine and tissue engineering, Stem Cell Reports encourages the submission of manuscripts whose scope bridges these fields of research. The journal also encourages the submission of reports of robust new methodologies with biological significance and/or the potential to advance the application of basic research from the laboratory to the clinic. Stem Cell Reports promotes transparency in stem cell research and related fields of research through the publication of confirmatory findings, negative results, and adverse events.
Stem Cell Reports covers:
- Embryonic stem cells
- Adult stem cells
- Reprogramming to pluripotency and lineage conversion
- Directed differentiation
- Germ cells
- Genetic and epigenetic mechanisms
- Stem cells in development
- Stem cell niche
- Cancer stem cells
- Disease modeling and drug screening
- Stem cell therapy
- Clinical studies in regenerative medicine
- Tissue engineering and biomaterials
- Imaging and diagnostics
- Stem cell products, manufacturing, and quality control
- Ethical, legal, and social issues
Instructions to Authors
Stem Cell Reports was launched in June 2013. It is published by Cell Press for the International Society for Stem Cell Research (ISSCR) and is intended as an open access forum communicating basic discoveries in stem cell research, in addition to translational and clinical studies. In addition to full length articles, Stem Cell Reports features shorter, single-point manuscripts that report original research with conceptual or practical advances of broad interest to stem cell biologists and clinicians.
Editorial Evaluation Timeline
All submissions are initially evaluated in depth by the scientific editors. Papers that are not deemed by the editors to be strong candidates for publication will be returned to the authors without detailed review, typically within 3–5 days. Otherwise, manuscripts will be sent to reviewers who have agreed in advance to assess the paper rapidly. The editors will make every effort to reach decisions on these papers within 3–4 weeks of the submission date. If revisions are required, editors will carefully evaluate the reviewers' comments and, whenever possible, will provide guidance on the important concerns to be addressed. We generally allow 3 months for revisions and consider only one revised version of the paper. Accepted papers will be published online within 6 weeks of acceptance. Any major changes after acceptance are subject to review and may delay publication.
Editorial Policies
Manuscripts are considered with the understanding that no part of the work has been published previously in print or electronic format and the paper is not under consideration by another publication or electronic medium. Prior publication could include, but is not limited to, deposition of all or part of the data in a publicly-accessible preprint or poster repository. Questions related to this policy should be directed to the editors at stemcellreports@isscr.org. All in-press or submitted works that are pertinent to the manuscript under consideration by the journal (including those cited in the manuscript under consideration) must accompany the submission. Any related manuscripts that have been submitted elsewhere during the period of revision must accompany revised manuscripts. Failure to provide copies of related manuscripts under consideration elsewhere may delay the review process and may be grounds for rejection. Under no circumstances will any paper be considered that contains any data that have been submitted for publication in another journal. Works under consideration for publication in Stem Cell Reports should not be submitted for publication elsewhere. Stem Cell Reports aims to increase the transparency of peer review and decision making. For this reason, reviewers will be notified when an editorial decision on a manuscript they reviewed has been made and each reviewer will receive the comments of all additional reviewers on the same manuscript.
Authorship
Corresponding Author: The corresponding author(s) is responsible for ensuring that all appropriate contributors are listed as authors and that all authors have agreed to the manuscript's content and its submission to Stem Cell Reports. In a case where we become aware of an authorship dispute, authorship must be approved in writing by all of the parties. The corresponding author(s) is also responsible for ensuring adherence to all editorial and submission policies and for any communications and actions that may be necessary after publication. Because of the responsibilities associated with this designation, a maximum of two corresponding authors is allowed. Exceptions will only be considered in cases of compelling need and by prior discussion with the handling editor.
Co-authorship Designations: In recognition of increasingly collaborative studies, up to two additional co-senior authors may be designated. All co-senior authors will be identified by a numeric footnote in the affiliations list, e.g., "5Co-senior author". Beyond co-senior and corresponding author designations (see above), co-authorship designations are only permitted for the first author position. There is no limitation on the number of authors that can be designated as co-first authors, but a description of each author's specific contribution must be provided in the Author Contributions section of the manuscript. All co-first authors will be identified by a numeric footnote in the affiliations list, e.g., "4Co-first author".
As the complexity and interdisciplinary nature of science grows and evolves, so do the networks of collaborations both within and between labs for published articles. While the author list at the start of a manuscript is not an appropriate or sufficient place to convey this increasingly complex information, all authors are encouraged to include the detailed information about the specific contributions of each author and laboratory in the Author Contributions section. For more information, please see "Author Contributions" under "Preparation of Specific Sections."
Conflict of Interest
Stem Cell Reports requires all authors to disclose any financial conflict of interest that might be construed to influence the results or interpretation of their manuscript. Authors must declare any such conflict in the cover letter accompanying the manuscript and in the Acknowledgments section of the manuscript itself. The corresponding author will be asked to sign a form on behalf of all of the authors regarding potential conflicts of interest at the time of acceptance. As a guideline, any affiliation associated with a payment or financial benefit exceeding $10,000 p.a. or 5% ownership of a company or research funding by a company with related interests would constitute a conflict that must be declared. This policy applies to all submitted research manuscripts and review material. Examples of statement language include: "AUTHOR is an employee and shareholder of COMPANY"; "AUTHOR is a founder of COMPANY and a member of its scientific advisory board"; "This work was supported in part by a grant from COMPANY."
Studies Involving Humans and Animals
For manuscripts reporting studies involving human subjects, statements identifying the committee approving the studies and confirming that informed consent was obtained from all subjects must appear in the Experimental Procedures section. All experiments on live vertebrates or higher invertebrates must be performed in accordance with relevant institutional and national guidelines and regulations. In the manuscript, a statement identifying the committee approving the experiments and confirming that all experiments conform to the relevant regulatory standards must be included in the Experimental Procedures section. The editors reserve the right to seek comments from reviewers or additional information from authors on any cases in which concerns arise. We suggest that researchers carrying out experiments with animals refer to the ARRIVE guidelines and recommendations from an NIH-sponsored workshop regarding experimental design and reporting standards.
Data Processing Policy
Authors should make every attempt to reduce the amount of postacquisition processing of data. Some degree of processing may be unavoidable in certain instances and is permitted provided that the final data accurately reflect that of the original. In the case of image processing, alterations must be applied to the entire image (e.g., brightness, contrast, color balance). In rare instances for which this is not possible (e.g., alterations to a single color channel on a microscopy image), any alterations must be clearly stated in the figure legend and in the Experimental Procedures section. Groupings and consolidation of data (e.g., cropping of images or removal of lanes from gels and blots) must be made apparent and should be explicitly indicated in the appropriate figure legends. Data comparisons should only be made from comparative experiments. Authors are discouraged from using images, blots, etc., or parts thereof, multiple times in separate figures (including the supplemental figures), because this can be interpreted as illegitimate duplication of data. Manuscripts containing duplicate figures/data will be returned to the authors for revision. In the event that it is deemed necessary for proper evaluation of the manuscript, authors will be required to make the original unprocessed data available to the editors of the journal.
Distribution of Materials and Data
One of the terms and conditions of publishing with Stem Cell Reports is that authors be willing to distribute any materials and protocols used in the published experiments to qualified researchers for their own use. Materials include but are not limited to cells, DNA, antibodies, reagents, organisms, and mouse strains or, if necessary, the relevant ES cells. These must be made available with minimal restrictions and in a timely manner, but it is acceptable to request reasonable payment to cover the cost of maintenance and transport of materials. If there are restrictions to the availability of any materials, data, or information, these must be disclosed in the cover letter and in the Experimental Procedures section of the manuscript at the time of submission.
Data sets must be made freely available to readers from the date of publication upon request and must be provided to editors and peer reviewers at submission for the purposes of evaluating the manuscript.
For the following types of data, submission of the full data set to a community-endorsed, public repository is mandatory. Accession numbers must be provided in the paper at the end of the Experimental Procedures section. Examples of appropriate public repositories are listed below.
DNA, RNA, and Protein Sequences
Protein Sequences: Uniprot
DNA and RNA Sequences: Genbank/European Nucleotide Archive (ENA)/DDBJ, Protein DataBank, UniProt
DNA Sequencing Data (traces and short reads): NCBI Trace and Short-Read Archive, ENA's Sequence Read Archive
Deep Sequencing Data: Deposit in GEO or ArrayExpress upon submission to the journal
The sequences of all primers, RNAi, antisense, and morpholino probes must be included in the paper or deposited in a public database with the accession number provided in the paper.
Human genomic data reporting newly described SNPs and CNVs identified in control samples should be deposited in an appropriate repository such as dbSNP, the Database of Genomic Variants Archive (DGVa), or the Database of Genomic Structural Variation (dbVAR).
We encourage but do not require the deposition of human sequence data in an appropriate repository such as dbGaP. We expect that, if data collected for a published paper cannot be included in the paper or made accessible in a public repository, then authors will accommodate legitimate requests for sharing of human genetics data provided that there are no IRB restrictions.
Microarray Data
MIAME-Compliant Microarray Data: GEO or ArrayExpress upon submission to the journal
Data must be MIAME compliant, as described at the MGED website specifying microarray standards.
Other Data Sets
In addition to the information that must be deposited in public databases as detailed above, authors are encouraged to contribute additional information to the appropriate databases. Authors are also encouraged to deposit materials used in their studies in the appropriate repositories for distribution to researchers.
Examples of repositories that facilitate sharing large data sets, including some that offer the option of anonymous referee access to data before publication, include:
For proteomics data: PRIDE, PeptideAtlas
For protein interaction data: IMEx consortium of databases, including DIP, IntAct, and MINT
For chemical compound screening and assay data: PubChem
Where there is no public repository and if the data sets are too large to submit to the journal online, authors should either consult the journal editorial office for advice or provide five separate copies of these data to the editors in an appropriate format (for example, CD or DVD) for the purposes of peer review.
Open Access/Copyright Policy
Authors will be asked to sign a nonexclusive publishing agreement that allows them to retain copyright of their work. Authors can choose to publish their work under one of two Creative Common licenses.
The first option is the Creative Commons Attribution 3.0 Unported License, which allows users to alter and build upon the article and then distribute the resulting work, even commercially. As with all Creative Commons licenses the work must be attributed to the original author and publisher. This license encourages maximum use and redistribution. The full details of the license are available at http://creativecommons.org/licenses/by/3.0/legalcode.
The second option is the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which allows users to copy and distribute the article, provided the work is attributed back to the original author and publisher. The article cannot be changed in any way or used commercially. The full details of the license are available at http://creativecommons.org/licenses/by-nc-nd/3.0/legalcode.
Publication Fee
To provide open access, expenses are offset by a publication fee of $3500 (USD) or $3000 (USD) for ISSCR members that will allow Stem Cell Reports to support itself in a fully sustainable way. This publication charge is the only fee that is requested. Stem Cell Reports will consider reducing or waiving author fees for those who have difficulties with the fee, on a case-by-case basis.
Some universities have signed the Compact for Open-Access Publishing Equity (COPE): "the timely establishment of durable mechanisms for underwriting reasonable publication charges for articles written by its faculty and published in fee-based open-access journals and for which other institutions would not be expected to provide funds." More information about COPE and the list of signatories can be found at http://www.oacompact.org. A list of institutions that provide funding for open access can be found at http://www.arl.org/sparc/bm~doc/oa-funds-in-action-attachment.pdf.
US National Institutes of Health (NIH) Posting Policy
As a service to Stem Cell Reports authors, our publisher Cell Press will deposit to PubMed Central (PMC) author manuscripts on behalf of Stem Cell Reports authors reporting National Institutes of Health (NIH)-funded research. The service will help authors comply with the NIH revised ''Public Access Policy',' effective April 7, 2008. The NIH's revised policy requires that NIH-funded authors submit to PMC, or have submitted on their behalf, their peer-reviewed author manuscripts, to appear on PMC no later than 12 months after final publication. Publication in Stem Cell Reports ensures compliance with this policy.
Wellcome Trust Funding
Authors whose work has been funded by the Wellcome Trust, a UK funding agency, are required to submit an electronic copy of any newly published research paper into PubMed Central (PMC). The Wellcome Trust requires that the work be made freely available to the public, via PMC, no later than six months after the official date of final publication. Publication in Stem Cell Reports ensures compliance with this policy.
Permissions
If excerpts from other copyrighted works are included in your manuscript, you must obtain written permission from the copyright owners and credit the sources in your article. To obtain permission to use material from Cell Press and Elsevier journals and books, please see the Cell Press Permissions page. If you have adapted a figure from a published figure, please check with the copyright owners to see if permission is required and include a complete citation/reference for the original article. Obtaining permissions can take up to several weeks. As lack of appropriate permissions can delay publication, we recommend that you request permission at the time of submission. Note that the permissions that you request must reflect the terms of the Creative Commons license under which the article will be published.
Prepublication Publicity
Work intended for submission to Stem Cell Reports, currently under consideration at Stem Cell Reports, or in press at Stem Cell Reports journal may not be discussed with the media before publication. All Stem Cell Reports papers will remain under media embargo until 12 PM NOON (US, EST) on their date of publication. Providing preprints, granting interviews, discussing data with members of the media, or participating in press conferences in advance of online publication without prior approval from the Cell Press editorial office may be grounds for rejection. With regards to the scientific literature, papers in press with Stem Cell Reports should not be discussed in reviews elsewhere prior to the date of online publication. Authors are welcome to present and discuss material intended for publication with Stem Cell Reports at scientific meetings; however, we do require that they refrain from discussing the findings with members of the press beyond those included in the formal presentation. In addition, we encourage meeting organizers to contact our editorial office in advance of a meeting if they have any questions regarding this policy. Any questions or issues regarding prepublication publicity should be directed to Press Officer Mary Beth O'Leary (moleary@cell.com).
Interaction with Members of the Press for Papers in Press
Authors are free to talk with the press one week prior to online publication, provided any information exchanged is embargoed until 12 PM NOON (US, EST) on the day of online publication. Authors may also discuss their work in press under embargo with other scientific journals for purposes of coverage in review material. Please refer any inquiries from media contacts and other journals to us. If your institutional press office wishes to issue a press release, they should contact us in advance for final embargo information. Any questions or issues regarding interaction with the press should be directed to Press Officer Mary Beth O'Leary (moleary@cell.com).
Research Article Formats
All research article formats are handled through our online submission system, Editorial Manager. A brief description of each article type is provided below. Please refer to "Preparation of Online Submission of Research Manuscripts" below for detailed information on the organization of research articles and their submission.
Reports
Reports cover a single point of strong significance that can be presented clearly within a shorter format. The total character count should be under 32,000 characters (including spaces, title page, references, and figure legends) and there should be no more than 4 figures and/or tables. Additional items may be published online as Supplemental Information at the discretion of the editor.
Research Articles
Research Articles present conceptual advances of unusual significance regarding an important biological question of wide interest to a particular community. Research papers should be as concise as possible and written in a style that is accessible to the broad Stem Cell Reports readership. The total character count of an article must be under 55,000 (including spaces, title page, references, and figure legends), and there should be no more than seven figures and/or tables. Additional display items may be published online as Supplemental Information at the discretion of the editor (please see the Supplemental Information guidelines for more information).
Resource Articles
The Resource format is designed to highlight significant technical advances or other resources that are of value and interest to the broad Stem Cell Reports readership. Resource articles are organized like Research Articles, have the same limits on length and figure/table number, and should be presented to be accessible to the broad Stem Cell Reports readership.
Preparation and Online Submission of Research Articles
Stem Cell Reports requires authors to submit manuscripts via our online submission system, Editorial Manager. An author tutorial regarding online submission is available at the Editorial Manager website.
Editorial Manager will prompt you to upload the individual components of your manuscript (cover letter, text, figures, Supplemental Information, etc.) as separate files. Upon completion of this step, the website will build a composite PDF file of your entire manuscript that will contain links for the editors and reviewers to download the individual high-resolution files of each component. Please note that the version of the PDF file that is accessible to reviewers does not contain the cover letter; any information therein will remain confidential.
Please be aware that Editorial Manager will send all communications about the paper (including the request for final approval and the confirmation of submission) to the person whose account is used to submit the manuscript. If you wish to specify a different author for editorial correspondence after submission, please contact the editorial office at stemcellreports@isscr.org.
Cover Letter
Each submission should be accompanied by a cover letter, which should contain a brief explanation of what was previously known, the conceptual advance provided by the findings, and the significance of the findings to a broad readership. A cover letter may contain suggestions for appropriate reviewers and up to three requests for reviewer exclusions. Suggested reviewers should not have been involved in any collaboration with the authors during the last 5 years. The cover letter is confidential to the editor and will not be seen by reviewers.
General Article Organization and Text Specifications
All three article types—Reports, Articles, and Resources—generally contain the following sections in this order: Title, Author List, Affiliations, Author Footnotes, Contact Information, Running Title, Summary, Introduction, Results, Discussion, Experimental Procedures, Acknowledgments, References, Figure Titles and Legends, Tables. The text (Title through Tables) should be provided as one document. Figures should be provided separately. Supplemental Information should be provided separately.
Manuscript file types that we can accept for submission include *.doc, *.docx, or *.rtf. Please note that the text should be double-spaced and pages should be numbered. Although summaries need to be entered as text files separate from the body of the manuscript during the online submission process, they should also be included within the manuscript file as usual. Manuscripts that do not conform to the format guidelines may be returned to the authors for reformatting.
Nomenclature
As a general rule, official symbols for genes and proteins rather than aliases should be used (see http://www.ncbi.nlm.nih.gov/gene for reference). Gene symbols should be italicized and spelled in capital letters for human genes, or with the first letter in capitals for mouse genes. Protein symbols are not italicized and are spelled in capital letters (applies to both human and mouse). For further information on nomenclature rules, go to http://www.informatics.jax.org/mgihome/nomen/gene.shtml (mouse/rat), http://www.genenames.org/ (human), http://zfin.org/ (zebrafish), or http://flybase.org (drosophilia).
Statistics and Controls
Quantitative data should be supported by adequate statistics. Specifically, the authors should report number and type of replicates “n” (e.g., technical replicates, independent experiment, mice, etc.) in the figure legends. Error bars should be defined as SD or SEM and statistical tests should be described in the Experimental Procedures or legends. Statistical tests should be performed for all key experiments and significance levels should be reported in the form of p-values where appropriate. Please note that statistical tests should be performed with at least three independent biological replicates.
Manuscripts reporting on the derivation and characterization of induced pluripotent stem cells (iPSCs) should include data on minimally 3 clones derived from at least 2 patients and 2 healthy control donors each. These numbers may be smaller for patients with very rare diseases or when performing genetic rescue experiments.
Fluorescence activated cell sorting (FACS) experiments should include appropriate negative controls, i.e., isotype antibodies rather than unstained cells should be used.
Please note that manuscripts will be returned to the authors before publication to complete missing or incomplete information on statistics and controls or to adjust nomenclature.
Preparation of Specific Sections
Title
Titles can occupy no more than three lines of type. Each line should contain no more than 50 characters, including spaces. The title should convey the conceptual significance of the paper to a broad readership.
Authors/Affiliations
Author names should be spelled out rather than set in initials. Authors should be footnoted to corresponding affiliations. Affiliations should contain the following core information: department(s)/subunit(s); institution; city, state/region, postal code; country. Note: Please check author names and affiliations carefully, as we cannot amend or correct these sections after publication.
Contact
The contact line should include the e-mail address of the corresponding author. The published corresponding author is responsible for ensuring adherence to all editorial and submission policies and for any communications that may result after publication. One corresponding author is preferred, but two are allowed.
Additional Footnotes
Footnotes are only allowed on page 1 of the text (and in tables). They may include a present address or may indicate co-first or co-senior authorship. For more on designations of author contributions, please see the "Authorship" section above, under Editorial Policies.
Running Title
The running title should be based on the title and should contain no more than 50 characters, including spaces.
Summary
The Summary consists of a single paragraph of fewer than 150 words. It should clearly convey the conceptual advance and significance of the work to a broad readership. In particular, the Summary should contain a brief background of the question, a description of the results without extensive experimental detail, and a summary of the significance of the findings. References should not be cited in the Summary.
Highlights and eTOC Blurb
Highlights are a short collection of bullet points that convey the core findings of the article. Specifications: up to four bullet points may be included; the length of an individual bullet point should not exceed 85 characters (including spaces); only the core results of the paper should be covered.
The eTOC blurb is a short summary of the main take-home message of the paper and should describe the context and significance of the findings for the broader readership. Please see the "In Brief" links in the Table of Contents for examples. Specifications: This blurb should be 60 words or fewer; this blurb should be written in the third person and refer to "Corresponding author and colleagues".
Both are required for all research papers and will be displayed online with the article; however, they will not appear in print. On the EM page where you are asked to upload your files, please choose "Highlights and eTOC Blurb" and upload a single Word document containing both your Highlights and eTOC blurb.
Introduction
The Introduction should be succinct, with no subheadings, and should present the background information necessary to provide a biological context for the results.
Results
This section should be divided with subheadings. Footnotes should not be used.
Discussion
The Discussion should explain the significance of the results and place them into a broader context. It should not be redundant with the Results section. Subheadings may be used but should be avoided if possible. Do not cite figures or tables in this section. Note that for Reports, the Results and Discussion sections may be combined at the authors' or editors' discretion.
Experimental Procedures
The Experimental Procedures section needs to include sufficient detail so that readers can understand how the experiments were done and so that all procedures can be repeated, in conjunction with cited references. This section should also include a description of any statistical methods employed in the study. A more detailed version of the procedures and details such as oligo sequences, strains, and specifics of how constructs were made can be included in the Supplemental Information, but it is not appropriate to move the majority of the Experimental Procedures to Supplemental Information in order to shorten the text. Please see our complete Supplemental Information guidelines for more information.
Author Contributions
We strongly encourage inclusion of a section describing the contributions of each author, designated by initials. For the case of co-first authors, a description of each author’s contribution is required.
Acknowledgments
This section may acknowledge contributions from non-authors and/or list funding sources, and it should include a statement of any conflicts of interest. Please check this section carefully, as we are unlikely to make amendments or corrections after publication.
References
References should include only articles that are published or in press. For references to in press articles, please confirm with the cited journal that the article is in fact accepted and in press and include a DOI number and online publication date. Unpublished data, submitted manuscripts, abstracts, and personal communications should be cited within the text only. Personal communication should be documented by a letter of permission. Submitted articles should be cited as unpublished data, data not shown, or personal communication.
Please use the style shown below for references. Note that "et al." should only be used after ten authors.
Article in a periodical:
Sondheimer, N., and Lindquist, S. (2000). Rnq1: an epigenetic modifier of protein function in yeast. Mol. Cell 5, 163–172.
Article in a book:
King, S.M. (2003). Dynein motors: Structure, mechanochemistry and regulation. In Molecular Motors, M. Schliwa, ed. (Weinheim, Germany: Wiley-VCH Verlag GmbH), pp. 45–78.
An entire book:
Cowan, W.M., Jessell, T.M., and Zipursky, S.L. (1997). Molecular and Cellular Approaches to Neural Development (New York: Oxford University Press).
In press article:
Demireva, E.Y., Shapiro, L.S., Jessell, T.M., and Zampier, N. (2011). Cell. Published online October 28, 2011. 10.1016/j.cell.2011.09.037
Figure Legends
Legends should be included in the submitted manuscript as a separate section. Each figure legend should have a brief title that describes the entire figure without citing specific panels, followed by a description of each panel. For any figures presenting pooled data, the measures should be defined in the figure legends (for example, "Data are represented as mean ± SEM."). Each legend should refer to any supporting items in the Supplemental Information (e.g., "See also Figure S1.").
Tables
When creating a table, please use the Microsoft Word Table function. Tables should include a title, and footnotes and/or legend should be concise. Include tables in the submitted manuscript as a separate section. Tables not created with the Microsoft Word table function will need to be revised by the author.
When creating tables, please adhere to the following guidelines:
- Do not submit tables in Excel or PDF format. Do not place an Excel table in a Word document.
- Format tables with Word's Table function; do not use tabs or spaces to create a table.
- Do not use line breaks or spaces to separate data within a cell. Use separate cells for all discrete data elements within a table.
- Number tables as Table 1, Table 2, Table 3, etc., rather than as Table 1a, Table 1b, Table 1c, etc.
- Tables should include a title above the table and a legend and/or footnotes below. The legend and/or footnotes should be concise.
- If bold or italic font is used within a table to indicate some feature of the data, please give an explanation of its usage in the legend.
- All abbreviations within a table must be defined in the table legend or footnotes.
- Footnotes should be listed with superscript lowercase letters, beginning with “a.” Footnotes may not be listed with numbers or symbols.
Supplemental Information
In general, Supplemental Information is limited to data and other materials that directly support the main conclusions of a paper but cannot be included in the main paper for reasons such as space or file format restrictions. SI should not be used to present data that are preliminary or that conceptually go beyond the main point of the paper.
Before submitting your supplemental materials, please refer to our complete instructions in the Supplemental Information guidelines. This page also contains information on submitting movie and other multimedia files.
Figures and Graphical Abstracts
Digital figure files must conform to our digital figure guidelines or authors will be asked to revise them. For Stem Cell Reports, we prefer TIFs or JPEGs for initial figure submission. In addition, before creating your figures, please carefully read the paragraph on Data Processing in our Editorial Policy section at the top of this page.
If you have any questions about digital files, please contact Diana Oesterle, Journal Manager of Stem Cell Reports, at doesterle@cell.com.
Graphical Abstract
A graphical abstract should allow readers to quickly gain an understanding of the main take-home message of the paper and is intended to encourage browsing, promote interdisciplinary scholarship, and help readers identify more quickly which papers are most relevant to their research interests. Graphical abstracts may be submitted at any stage but are only required once a paper has been accepted for publication (it is not necessary to provide a graphical abstract for a new submission). Graphical abstracts can be uploaded in Editorial Manager by selecting "Graphical Abstract" when uploading files. Refer to our digital figure guidelines for graphical abstract preparation details.
Submission of Revised Manuscripts
In addition to the sections described above, revised manuscripts must also contain a detailed point-by-point response to the comments of the reviewers and/or editors. The cover letter should briefly summarize how the revised manuscript addresses these comments.
Checklist for Final Submission
1. Please make sure your final manuscript:
- Meets the length and figure/table limits specified above for Reports, Research Articles, or Resource Articles
- Includes database accession numbers for new gene sequences, protein sequences, structures, or microarray data
- Includes explanation of statistical methods and sufficient detail of procedures in the Experimental Procedures section
- For any figures presenting pooled data, defines the replicates and the measures in the figure legend
2. Please submit your final materials through Editorial Manager.
3. Please include all of the following when you are resubmitting your final materials:
- A modifiable electronic version of the final text (Microsoft Word .docx file is preferred)
- A companion file containing the article Highlights and eTOC blurb
- High-resolution digital files of the main and supplemental figures in an accepted format (see digital figure guidelines)
- Supplemental Information set and submitted as outlined in the Supplemental Information guidelines
- Additional Supplemental Information files such as movies and spreadsheets
- Signed conflict of interest form and journal publishing agreement (please refer to your Editorial Manager letter for a link to this form)
- An online summary of 50-60 words to accompany your article on our journal homepage (please cite your article using the corresponding author(s) lastname(s); e.g., "In this article, [corresponding author] and colleagues...")
- Cover letter
Production and Proofs
After final acceptance, your manuscript will be passed to our production team to be copyedited and prepared for publication. Figures may be resized during the production process.
You will be contacted by a copyeditor after your paper enters production, and s/he will ask you some pre-proof questions related to the editing of your text. These questions should be answered within 24 hours in order to maintain the production schedule. After the copyediting queries have been resolved, you will receive PDF proofs via email within 5–10 days. The proofs will need to be returned with all vital corrections no more than 24 hours after receipt.
If you will be unreachable at all during this period or anticipate any problems meeting this timeline, please contact Diana Oesterle, Journal Manager (doesterle@cell.com).
Editorial Board
Submission Assistance and Inquiries about Submitted Manuscripts
E-mail: stemcellreports@isscr.org
Mailing Address
Department of Anatomy and Embryology
Leiden University Medical Center
Postal Zone: S-1-P
P.O. Box 9600
2300 RC Leiden
The Netherlands
Proofs and Other Production Questions
E-mail: Diana McKinney Oesterle, Journal Manager, doesterle@cell.com
Society Membership
International Society for Stem Cell Research
5215 Old Orchard Road, Suite 270
Skokie, IL 60077 USA
Phone: +1 224 592 5700
Fax: +1 224 365 0004
E-mail: isscr@isscr.org
Web: www.isscr.org/join
For the full Masthead and Editorial Board, click here.
Press Office
E-mail: Joseph Caputo, Media Relations Manager 
Advertising and Sponsorship
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Permissions
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