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期刊名称:PLOS PATHOGENS

ISSN:1553-7366
出版频率:Monthly
出版社:PUBLIC LIBRARY SCIENCE, 1160 BATTERY STREET, STE 100, SAN FRANCISCO, USA, CA, 94111
  出版社网址:http://biology.plosjournals.org/perlserv/?request=index-html&issn=1545-7885
期刊网址:http://pathogens.plosjournals.org/perlserv/?request=index-html&issn=1553-7374
影响因子:6.823
主题范畴:MICROBIOLOGY;    PARASITOLOGY;    VIROLOGY

期刊简介(About the journal)    投稿须知(Instructions to Authors)    编辑部信息(Editorial Board)   



About the journal

About PLoS Pathogens

PLoS Pathogens (eISSN 1553-7374, ISSN 1553-7366) is an open-access, peer-reviewed journal published monthly by the Public Library of Science (PLoS), a nonprofit organization.

PLoS Pathogens is run by an international Editorial Board, headed by the Editor-in-Chief, John A. T. Young (The Salk Institute for Biological Studies, La Jolla, California, United States).

Scope

Bacteria, fungi, parasites, prions and viruses cause a plethora of diseases that have important medical, agricultural, and economic consequences. Moreover, the study of microbes continues to provide novel insights into such fundamental processes as the molecular basis of cellular and organismal function.

PLoS Pathogens reflects the full breadth of research in these areas by publishing outstanding original articles that significantly advance the understanding of pathogens and how they interact with their host organisms. Topics include (but are not limited to) adaptive and innate immune defenses as well as pathogen countermeasures, emerging pathogens, evolution, genomics and gene regulation, model host organisms, pathogen-cell biology, pathogenesis, prions, proteomics and signal transduction, rational vaccine design, structural biology, and virulence factors.

Please refer to our Author Guidelines when you are preparing your manuscripts for submission. If you are unsure whether your paper is suitable for PLoS Pathogens, you can send a Presubmission Inquiry.

Open Access

All works published in PLoS journals are open access, licensed under the Creative Commons Attribution License. Everything is immediately available online without cost to anyone, anywhere¡ªto read, download, redistribute, include in databases, and otherwise use¡ªsubject only to the condition that the original authorship is properly attributed. Copyright is retained by the author.

Publication Charges

To provide open access, PLoS journals use a business model in which our expenses¡ªincluding those of peer review, journal production, and online hosting and archiving¡ªare recovered in part by charging a publication fee to the authors or research sponsors for each article they publish. For PLoS Pathogens the publication fee is US$2100. Authors who are affiliated with one of our Institutional Members are eligible for a discount on this fee.

We offer a complete or partial fee waiver for authors who do not have funds to cover publication fees. Editors and reviewers have no access to payment information, and hence inability to pay will not influence the decision to publish a paper.

For further information, see our Publication Fee FAQ.

About the Public Library of Science

The Public Library of Science (PLoS) is a non-profit organization of scientists and physicians committed to making the world's scientific and medical literature a freely available public resource. For more information about PLoS, visit www.plos.org.


Instructions to Authors

PLoS Pathogens Guidelines for Authors

Contents:

  1. About PLoS Pathogens
  2. Criteria for Publication
  3. Overview of the Editorial Process
  4. Presubmission Inquiries
  5. Preparation of Research Articles
  6. First-Time Submission of Research Articles
  7. Submission of Revised Research Articles
  8. Outline of the Production Process
  9. Other Types of Articles

1. About PLoS Pathogens

Bacteria, fungi, parasites, prions and viruses cause a plethora of diseases that have important medical, agricultural, and economic consequences. Moreover, the study of microbes continues to provide novel insights into such fundamental processes as the molecular basis of cellular and organismal function. PLoS Pathogens reflects the full breadth of research in these areas by publishing outstanding original articles that significantly advance the understanding of pathogens and how they interact with their host organisms. PLoS Pathogens provides immediate free access to all content, ensuring that authors reach the widest possible audience as soon as a manuscript is published. Topics include (but are not limited to) adaptive and innate immune defenses as well as pathogen countermeasures, emerging pathogens, evolution, genomics and gene regulation, model host organisms, pathogen-cell biology, pathogenesis, prions, proteomics and signal transduction, rational vaccine design, structural biology, and virulence factors.

To provide open access, PLoS journals use a business model in which our expenses¡ªincluding those of peer review, journal production, and online hosting and archiving¡ªare recovered in part by charging a publication fee to the authors or research sponsors for each article they publish. For PLoS Pathogens the publication fee is US$2100. Authors who are affiliated with one of our Institutional Members are eligible for a discount on this fee.

We offer a complete or partial fee waiver for authors who do not have funds to cover publication fees. Editors and reviewers have no access to payment information, and hence inability to pay will not influence the decision to publish a paper.

For further information, see our Publication Fee FAQ.

2. Criteria for Publication

To be considered for publication in PLoS Pathogens, any given manuscript must satisfy the following criteria:

  • Originality
  • High importance and broad interest to the community of researchers studying pathogens and pathogen-host interactions
  • Rigorous methodology
  • Substantial evidence supporting its conclusions

3. Overview of the Editorial Process

Our aim is to provide all authors with an efficient, courteous, and constructive editorial process. To achieve its required level of quality, PLoS Pathogens is highly selective in the manuscripts that it publishes. To ensure the fairest and most objective decision-making, the editorial process is run as a partnership between the PLoS Pathogens Editor-in-Chief, a team of Section Editore, and a group of academic experts who act as Associate Editors (AEs). These individuals are leaders in their fields and represent the full breadth of pathogen-related research.

Submitted manuscripts are assigned to an AE by the EIC or by one of the Section Editors. The AE is most often a member of the PLoS Pathogens Editorial Board but occasionally a guest of the Board is invited to serve in this capacity. The AE promptly evaluates the paper and decides whether it is likely to meet the requirements of providing a major advance in a particular field and describing a sufficient body of work to support that claim. If so, the paper is sent out for peer review.

Expert reviewers assess the technical and scientific merits of the work. Once all reviews have been received and considered by the editors, a decision letter to the author is drafted.

There are several types of decisions possible:

  • Accept without revision
  • Minor revision
  • Major revision
  • Reject, typically because the paper does not meet the criteria outlined above

If the decision is to invite resubmission, the author is advised in the decision letter whether the paper requires further peer review at that time.

4. Presubmission Inquiries

When authors are unsure whether their work satisfies the basic requirements for publication in PLoS Pathogens, we are happy to consider presubmission inquiries. If you wish to submit an informal presubmission inquiry to see if a manuscript is appropriate, please login or register at pathogens.plosjms.org, click the link labeled, "Submit Manuscript" and select Presubmission Inquiry as your article type.

Responses to these inquiries are normally provided within two or three working days. Responses may take longer if consultation between members of the editorial board is required. Authors who receive an invitation to submit their manuscript then enter the regular editorial process, but we cannot guarantee that manuscripts will then be approved for in-depth review.

5. Preparation of Research Manuscripts

PLoS Pathogens encourages the submission of both substantial full-length bodies of work and shorter manuscripts that report novel findings that might be based on a more limited range of experiments. The work must demonstrate its novelty, its importance to a particular field¡ªas well as its interest to those outside that discipline¡ªand conclusions that are justified by the study.

The writing style should be concise and accessible. Editors may make suggestions for how to improve clarity and readability, as well as to strengthen the argument. Our aim is to make the editorial process rigorous and consistent, but not intrusive or overbearing. Authors are encouraged to use their own voice and to decide how best to present their ideas, results, and conclusions.

Although we encourage submissions from around the globe, we require that manuscripts be submitted in English. As a step towards overcoming language barriers, we encourage authors fluent in other languages to provide copies of their full articles or abstracts in other languages. Translations should be submitted as supporting information and listed, together with other supporting information files, at the end of the article text.

Organization of the Manuscript

Most articles published in PLoS Pathogens are organized into the following sections: Title, Authors, Affiliations, Abstract, Introduction, Results, Discussion, Materials and Methods, Acknowledgments, References, and Figure Legends. Uniformity in format facilitates the experience of readers and users of the journal. Abstracts should not exceed 250-300 words. There are no specific length restrictions for the overall manuscript or individual sections; however, we urge authors to present and discuss their findings succinctly.

If your research article is accepted for publication, you will be asked to provide an author summary¡ªa 150-200 word lay summary of the work that places the findings in a broader context and makes the work accessible to a wide audience.

Our submission system supports a limited range of formats for text and graphics. If you experience difficulties with the manuscript submission Web site or are concerned about the suitability of your files, please contact the journal (plospathogens [at] plos.org).

Title (75 characters or less)

The title should be specific to the project, yet concise. It should be comprehensible to readers outside your field. Avoid specialist abbreviations, if possible. Titles should be presented in title case, meaning that all words except for prepositions, articles, and conjunctions should be capitalized.

Please also provide a brief "running head" of approximately 40 characters.

Authors and Affiliations

Provide the first names or initials (if used), middle names or initials (if used), surnames, and affiliations¡ªdepartment, university or organization, city, state/province (if applicable), and country¡ªfor all authors. One of the authors should be designated as the corresponding author. It is the corresponding author¡¯s responsibility to ensure that the author list, and the summary of the author contributions to the study are accurate and complete. If the article has been submitted on behalf of a consortium, all consortium members and affiliations should be listed after the Acknowledgments.

Abstract

The abstract of the paper should be succinct; it should not exceed 250-300 words. Authors should mention the techniques used without going into methodological detail and should summarize the most important results. The abstract is conceptually divided into the following three sections: Background, Methodology/Principal Findings, and Conclusions/Significance. Please do not include any citations and avoid specialist abbreviations.

Introduction

The introduction should put the focus of the manuscript into a broader context. As you compose the introduction, think of readers who are not experts in this field. Include a brief review of the key literature. Relevant controversies or disagreements in the field should be mentioned so that a non-expert reader can delve into these issues further. The introduction should conclude with a brief statement of the overall aim of the experiments and a comment about whether that aim was achieved.

Results

The results section should provide details of all of the experiments that are required to support the conclusions of the paper. Details of experiments that are peripheral to the main thrust of the article and that detract from the focus of the article, however, should not be included. The section may be divided into subsections, each with a concise subheading. Large datasets, including raw data, should be submitted as supporting files; these are published online alongside the accepted article. The results section should be written in past tense.

Discussion

The discussion should spell out the major conclusions of the work along with some explanation or speculation on the significance of these conclusions. How do the conclusions affect the existing assumptions and models in the field? How can future research build on these observations? What are the key experiments that must be done? The discussion should be concise and tightly argued. The results and discussion may be combined into one section, if desired.

Materials and Methods

This section should provide enough detail for reproduction of the findings. Protocols for new methods should be included, but well-established protocols may simply be referenced. We encourage authors to submit, as separate supporting information files, all appendices, detailed protocols, or details of the algorithms for newer or less well-established methods. These are published online only, but are linked to the article and are fully searchable.

Acknowledgments

People who contributed to the work, but do not fit the criteria for authors should be listed in the Acknowledgments, along with their contributions. You must also ensure that anyone named in the acknowledgments agrees to being so named.

Funding

This section should describe sources of funding that have supported the work. Please also describe the role of the study sponsor(s), if any, in study design; collection, analysis, and interpretation of data; writing of the paper; and decision to submit it for publication.

References

Only published or accepted manuscripts should be included in the reference list. Meetings abstracts, conference talks, or papers that have been submitted but not yet accepted should not be cited. Limited citation of unpublished work should be included in the body of the text only. All personal communications should be supported by a letter from the relevant authors.

PLoS uses the numbered citation (citation-sequence) method. References are listed and numbered in the order that they appear in the text. In the text, citations should be indicated by the reference number in brackets. Multiple citations within a single set of brackets should be separated by commas. Where there are more than three sequential citations, they should be given as a range. Example: "...has been shown previously [1,4¨C6,22]." Make sure the parts of the manuscript are in the correct order for the relevant journal before ordering the citations. Figure captions and tables should be at the end of the manuscript.

Because all references will be linked electronically as much as possible to the papers they cite, proper formatting of the references is crucial. For all references, list the first five authors; add "et al." if there are additional authors. You can include a DOI number for the full-text article as an alternative to or in addition to traditional volume and page numbers. Please use the following style for the reference list:

Published Papers
1. Sanger F, Nicklen S, Coulson AR (1977) DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A 74: 5463¨C5467.

Accepted Papers
Same as above, but "In press" appears instead of the page numbers. Example: Adv Clin Path. In press.

Electronic Journal Articles 1. Loker WM (1996) "Campesinos" and the crisis of modernization in Latin America. Jour Pol Ecol 3. Available: http://www.library.arizona.edu/ej/jpe/volume_3/ascii-lokeriso.txt. Accessed 11 August 2006.

Books
1. Bates B (1992) Bargaining for life: A social history of tuberculosis. Philadelphia: University of Pennsylvania Press. 435 p.

Book Chapters
1. Hansen B (1991) New York City epidemics and history for the public. In: Harden VA, Risse GB, editors. AIDS and the historian. Bethesda: National Institutes of Health. pp. 21¨C28.

Accession Numbers

All appropriate datasets, images, and information should be deposited in public resources. Please provide the relevant accession numbers (and version numbers, if appropriate). Suggested databases include, but are not limited to:

In addition, as much as possible, please provide accession numbers or identifiers for all entities such as genes, proteins, mutants, diseases, etc., for which there is an entry in a public database, for example:

Providing accession numbers allows linking to and from established databases and integrates your article with a broader collection of scientific information. Please list all accession numbers directly after the Supporting Information section.

Abbreviations

Please keep abbreviations to a minimum. List all non-standard abbreviations in alphabetical order, along with their expanded form. Define them as well upon first use in the text. Non-standard abbreviations should not be used unless they appear at least three times in the text.

Nomenclature

The use of standardized nomenclature in all fields of science and medicine is an essential step toward the integration and linking of scientific information reported in published literature. We will enforce the use of correct and established nomenclature wherever possible:

  • We strongly encourage the use of SI units. If you do not use these exclusively, please provide the SI value in parentheses after each value.
  • Species names should be italicized (e.g., Homo sapiens).
  • Genes, mutations, genotypes, and alleles should be indicated in italics. Use the recommended name by consulting the appropriate genetic nomenclature database, e.g., HUGO for human genes. It is sometimes advisable to indicate the synonyms for the gene the first time it appears in the text. Gene prefixes such as those used for oncogenes or cellular localization should be shown in roman: v-fes, c-MYC, etc.
  • The Recommended International Non-Proprietary Name (rINN) of drugs should be provided.

Figures

If the article is accepted for publication, the author will be asked to supply high-resolution, print-ready versions of the figures. Please ensure that the files conform to our Guidelines for Figure and Table Preparation when preparing your figures for production. After acceptance, authors will also be asked to provide an attractive image to highlight their paper online.

Figure Legends

The aim of the figure legend should be to describe the key messages of the figure, but the figure should also be discussed in the text. An enlarged version of the figure and its full legend will often be viewed in a separate window online, and it should be possible for a reader to understand the figure without switching back and forth between this window and the relevant parts of the text. Each legend should have a concise title of no more than 15 words. The legend itself should be succinct, while still explaining all symbols and abbreviations. Avoid lengthy descriptions of methods.

Tables

All tables should have a concise title. Footnotes can be used to explain abbreviations. Citations should be indicated using the same style as outlined above. Tables occupying more than one printed page should be avoided, if possible. Larger tables can be published as online supporting information. Tables must be cell-based; do not use picture elements, text boxes, tabs, or returns in tables. Please ensure that the files conform to our Guidelines for Figure and Table Preparation when preparing your tables for production.

Multimedia and Other Supporting Files

We encourage authors to submit essential supporting files and multimedia files along with their manuscripts. All supporting material will be subject to peer review, and should be smaller than 10 MB in size because of the difficulties that some users will experience in loading or downloading files of a greater size.

Supporting files should fall into one of the following categories: Dataset, Figure, Table, Text, Protocol, Audio, or Video. All supporting information should be referred to in the manuscript with a leading capital S (e.g., Figure S4 for the fourth supporting information figure). Titles (and, if desired, legends) for all supporting information files should be listed in the manuscript under the heading "Supporting Information."

Supporting files may be submitted in a variety of formats, but should be publication-ready, as these files are not copyedited. All video files should be submitted as AVI or Quicktime files.

6. First-Time Submission of Research Articles

Cover Letter

It is important that you include a cover letter with your manuscript. Please explain why this manuscript is suitable for publication in PLoS Pathogens, why will your paper inspire the other members of your field, and how will it drive research forward.

Electronic Submission

Detailed instructions for submission can be found on the PLoS Pathogens Manuscript Submission and Peer Review Web site. For your initial submission, we recommend you upload your entire manuscript, including tables and figures, as a single PDF file. This will save you time in uploading and allows editors and reviewers to view and/or download your manuscript in one easy step. If you choose to upload files individually, they will be combined into a single PDF file that you must approve at the end of the submission process.

Electronic Formats

Text files can be submitted in the following formats: Word, RTF, or PDF. Any articles that have been prepared in LaTeX will be accepted for review, but only in PDF format. Post acceptance, text files (RTF or Word) of the revised manuscript and tables are required for use in the pre-production and copyediting processes. Graphics files can be submitted in the following formats: EPS, TIFF, or PDF.

Before submission, please consult our Submission Checklist.

7. Submission of Revised Research Articles

If you are invited to submit a revised manuscript, we will ask for an editable text and publication-quality files for display items (figures and tables) at that time. Together with your response to editors¡¯ and/or reviewers¡¯ comments, please provide an author summary of your work and a striking image (if one is available).

Author Summary

We ask that all authors of research articles that have been returned for revision include a 150-200 word non-technical summary of the work as part of the revised manuscript immediately following the Abstract. Subject to editorial review and author revision, this short text is published with all research articles as a highlighted text box.

Distinct from the scientific abstract, the author summary should highlight where the work fits in a broader context of life science knowledge and why these findings are important to an audience that includes both scientists and non-scientists.

Authors should avoid the use of acronyms and complex scientific terms and write the text using the first-person voice. Authors may benefit from consulting with a science writer or press officer to ensure they effectively communicate their findings to a general audience.

Examples of synopses are available at:

Using the TAP Component of the Antigen-Processing Machinery as a Molecular Adjuvant

The Beta-Glucan Receptor Dectin-1 Recognizes Specific Morphologies of Aspergillus fumigatus

Cytoskeletal Components of an Invasion Machine¡ªThe Apical Complex of Toxoplasma gondii

Issue Image

Authors are encouraged to provide a striking image (or multimedia clip) to accompany their article, if one is available. The image (or video clip) will be considered for publication as a "featured image" or article highlight on our Web site.

Before resubmission, please consult our Checklist for Revised Submissions.

8. Outline of the Production Process

Once an article has been accepted for publication, the manuscript files are transferred into our production system. Manuscripts are then copyedited by professional copyeditors who correspond directly with the authors concerning queries and corrections. Once the article has been typeset, PDF proofs are generated so that authors can approve all editing and layout. The prompt return of proofs by authors will expedite the production process.

Articles are published online weekly, before a complete issue is assembled each month. PLoS Pathogens aims to publish Research Articles within a month of acceptance, after copyediting, formatting, and proofreading.

9. Other Types of Articles

The front section of PLoS Pathogens is a forum for the publication of articles of broad interest to the community of researchers studying pathogens and pathogen-host interactions. Reviews and Opinions in the front section of PLoS Pathogens are published by invitation. If you have a suggestion for a topic or an author, we are happy to consider the idea. Please contact the editors (plospathogens [at] plos.org).


Editorial Board

PLoS Pathogens Editorial Board

For editorial inquiries, please e-mail plospathogens [at] plos.org.

Editor-in-Chief

John A. T. Young
Infectious Disease Laboratory
The Salk Institute for Biological Studies
San Diego, California, USA
E-mail: jyoung [at] plos.org

Deputy Editor

Kasturi Haldar
Northwestern University
Chicago, IL

Reviews Editor

Brett Finlay
University of British Columbia
Vancouver, BC

Opinions Editor

Marianne Manchester
The Scripps Research Institute
La Jolla, CA

Section Editors

Frederick M. Ausubel
Harvard Medical School
Boston, MA
Bacterial Pathogenesis
John Boothroyd
Stanford University School of Medicine
Palo Alto, CA
Parasite Pathogenesis
Brendan Cormack
Johns Hopkins School of Medicine
Baltimore, MD
Fungal Pathogenesis
Daniel E. Goldberg
Washington University School of Medicine
St. Louis, MO
Parasite Pathogenesis

Ralph Isberg
Tufts University School of Medicine
Boston, MA
Bacterial Pathogenesis
James Kazura
Case Western Reserve University School of Medicine
Cleveland, OH
Parasite Pathogenesis
Grant McFadden
University of Florida
Gainesville, FL
Viral Pathogenesis
David Westaway
University of Alberta
Edmonton, Canada
Prion Pathogenesis

Associate Editors

Mark Achtman
Max Planck Institute
Berlin, Germany
Ralph S. Baric
University of North Carolina
Chapel Hill, NC
Stephen M. Beverley
Washington University School of Medicine
St. Louis, MO
Paul Bieniasz
Rockefeller University
New York, NY
William Bishai
Johns Hopkins School of Medicine
Baltimore, MD
Michael J Buchmeier
The Scripps Research Institute
La Jolla, CA
Mark L. Buller
Saint Louis University
Saint Louis, MO
Barbara Burleigh
Harvard School of Public Health
Boston, MA
Pascale Cossart
Institut Pasteur
Paris, France
Jeff Dangl
The University of North Carolina At Chapel Hill
Chapel Hill, NC
Karen P. Day
NYU School of Medicine
New York, NY
Mary K. Estes
Baylor College of Medicine
Houston, TX
Scott G. Filler
Harbor-UCLA Medical Center
Torrance, CA
Klaus Frueh
Oregon Health and Sciences University
Beaverton, OR
Jorge Galan
Yale University School of Medicine
New Haven, CT
Donald Ganem
University of California, San Francisco
San Francisco, CA
Adolfo Garcia-Sastre
Mount Sinai School of Medicine
New York, NY
Partho Ghosh
University of California, San Diego
La Jolla, CA
Keith Gull
University of Manchester
Manchester, United Kingdom
Eddie C. Holmes
Pennsylvania State University
University Park, PA
Kathryn Holmes
University of Colorado
Denver, CO
Thomas J. Hope
Northwestern University
Chicago, IL
Scott J. Hultgren
Washington University School of Medicine
St. Louis, MO
Alexander Johnson
University of California, San Francisco
San Francisco, CA
Patricia Johnson
University of California, Los Angeles
Los Angeles, CA
Yoshihiro Kawaoka
University of Wisconsin-Madison and University of Tokyo
Madison, Wisconsin; Tokyo, Japan
Richard Koup
National Institutes of Health, National Institute of Allergy and Infectious Diseases
Bethesda, MD
Bruce Levin
Emory University
Atlanta, GA
Beth Levine
University of Texas-Southwestern Medical Center At Dallas
Dallas, TX
Jeremy Luban
Institute for Research in Biomedicine
Bellinzona, Switzerland
Neil A. Mabbott
Institute for Animal Health
Edinburgh, United Kingdom
Rick Maizels
University of Edinburgh
Edinburgh, United Kingdom
Michael H. Malim
King's College London, Guy's King's And St. Thomas' School of Medicine
London, United Kingdom
Daniel A. Portnoy
University of California, Berkeley
Berkeley, CA
Lalita Ramakrishnan
University of Washington
Seattle, WA
Charles M. Rice
The Rockefeller University
New York, NY
Eleanor M. Riley
London School of Hygiene & Tropical Medicine
London, United Kingdom
Susan R. Ross
University of Pennsylvania School of Medicine
Philadelphia, PA
Artur Scherf
Institute Pasteur
Paris, France
Olaf Schneewind
University of Chicago
Chicago, IL
David S. Schneider
Stanford University
Palo Alto, CA
L. David Sibley
Washington University School of Medicine
St. Louis, MO
Joseph Smith
Seattle Biomedical Research Institute
Seattle, WA
Dominique Soldati
Imperial College
London, United Kingdom
C. Erec Stebbins
Rockefeller University
New York, NY
Kanta Subbarao
National Institutes of Health
Bethesda, MD
Bill Sugden
University of Wisconsin-Madison
Madison, WI
Kenneth Vernick
University of Minnesota
Twin Cities, MN
Herbert "Skip" Virgin
Washington University School of Medicine
St. Louis, MO
Jeffrey Weiser
University of Pennsylvania
Philadelphia, PA
Michael Wessels
Harvard Medical School
Cambridge, MA


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